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URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

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URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

PCT NATIONAL PHASE APPLICATION

Published

date

Filed on 1 November 2024

Abstract

The present invention provides a compound showing coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same. A compound represented by formula (I) [in the formula: ring A is a ring represented by formula (I-A) (wherein X is a single bond, etc., R2 is a substituted or unsubstituted aromatic carbocyclic group, etc., and R3c is a substituted or unsubstituted aromatic carbocyclic group, etc.); R1 is a substituted or unsubstituted aromatic heterocyclic group; m is 0, etc.; R5as are independently a hydrogen atom, etc.; R5bs are independently a hydrogen atom, etc.; R6 is cyano, etc.; and R7a and R7b are independently a hydrogen atom, etc.], or a pharmaceutically acceptable salt thereof.

Patent Information

Application ID202447083680
Invention FieldCHEMICAL
Date of Application01/11/2024
Publication Number45/2024

Inventors

NameAddressCountryNationality
SATO Junc/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
SHIBAYAMA Hiromitsuc/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
HIRAI Keiichiroc/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
UNOH Yutoc/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
UEHARA Shotac/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
YONEZAWA Shujic/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
KURAHASHI Kanac/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan
KOJIMA Eiichic/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan

Applicants

NameAddressCountryNationality
SHIONOGI & CO., LTD.1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045JapanJapan

Documents

NameDate
202447083680-FORM-26 [04-11-2024(online)].pdf04/11/2024
202447083680-COMPLETE SPECIFICATION [01-11-2024(online)].pdf01/11/2024
202447083680-DECLARATION OF INVENTORSHIP (FORM 5) [01-11-2024(online)].pdf01/11/2024
202447083680-FORM 1 [01-11-2024(online)].pdf01/11/2024
202447083680-FORM 18 [01-11-2024(online)].pdf01/11/2024
202447083680-PRIORITY DOCUMENTS [01-11-2024(online)].pdf01/11/2024
202447083680-PROOF OF RIGHT [01-11-2024(online)].pdf01/11/2024
202447083680-REQUEST FOR EXAMINATION (FORM-18) [01-11-2024(online)].pdf01/11/2024
202447083680-Sequence Listing in PDF [01-11-2024(online)].pdf01/11/2024
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