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URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
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URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
PCT NATIONAL PHASE APPLICATION
Published
Filed on 1 November 2024
Abstract
The present invention provides a compound showing coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same. A compound represented by formula (I) [in the formula: ring A is a ring represented by formula (I-A) (wherein X is a single bond, etc., R2 is a substituted or unsubstituted aromatic carbocyclic group, etc., and R3c is a substituted or unsubstituted aromatic carbocyclic group, etc.); R1 is a substituted or unsubstituted aromatic heterocyclic group; m is 0, etc.; R5as are independently a hydrogen atom, etc.; R5bs are independently a hydrogen atom, etc.; R6 is cyano, etc.; and R7a and R7b are independently a hydrogen atom, etc.], or a pharmaceutically acceptable salt thereof.
Patent Information
| Application ID | 202447083680 |
| Invention Field | CHEMICAL |
| Date of Application | 01/11/2024 |
| Publication Number | 45/2024 |
Inventors
| Name | Address | Country | Nationality |
|---|---|---|---|
| SATO Jun | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| SHIBAYAMA Hiromitsu | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| HIRAI Keiichiro | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| UNOH Yuto | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| UEHARA Shota | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| YONEZAWA Shuji | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| KURAHASHI Kana | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
| KOJIMA Eiichi | c/o Shionogi & Co., Ltd., 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
Applicants
| Name | Address | Country | Nationality |
|---|---|---|---|
| SHIONOGI & CO., LTD. | 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 | Japan | Japan |
Documents
| Name | Date |
|---|---|
| 202447083680-FORM-26 [04-11-2024(online)].pdf | 04/11/2024 |
| 202447083680-COMPLETE SPECIFICATION [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-DECLARATION OF INVENTORSHIP (FORM 5) [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-FORM 1 [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-FORM 18 [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-PRIORITY DOCUMENTS [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-PROOF OF RIGHT [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-REQUEST FOR EXAMINATION (FORM-18) [01-11-2024(online)].pdf | 01/11/2024 |
| 202447083680-Sequence Listing in PDF [01-11-2024(online)].pdf | 01/11/2024 |
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