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SMALL MOLECULE ALLOSTERIC MODULATORS OF THE SEROTONIN (5-HT) 5-HT2C AND 5-HT2A RECEPTORS

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SMALL MOLECULE ALLOSTERIC MODULATORS OF THE SEROTONIN (5-HT) 5-HT2C AND 5-HT2A RECEPTORS

PCT NATIONAL PHASE APPLICATION

Published

date

Filed on 28 October 2024

Abstract

The present invention relates to novel 5HT receptor modulators, such as compounds of the general Formula (I) and general Formula (II): or a pharmaceutically acceptable salt thereof. Methods of using the compounds include, for example, modulation of 5-hydroxytryptamine (5-HT) receptor subtypes, including 5-hydroxytryptamine 2A receptor and/or 5-hydroxytryptamine 2C receptor, and treatment of a condition or disease where the treatment is associated with the modulation of 5-hydroxytryptamine 2A receptor and/or 5-hydroxytryptamine 2C receptor.

Patent Information

Application ID202447082192
Invention FieldCHEMICAL
Date of Application28/10/2024
Publication Number44/2024

Inventors

NameAddressCountryNationality
ZHOU, Jiac/o University of Texas Medical Branch 301 University Boulevard Galveston, TX 77555U.S.A.U.S.A.
CHEN, Jianpingc/o University of Texas Medical Branch 301 University Boulevard Galveston, TX 77555U.S.A.U.S.A.
WILD, Christopher, T.c/o University of Texas Medical Branch 301 University Boulevard Galveston, TX 77555U.S.A.U.S.A.
ANASTASIO, Noelle, C.c/o University of Texas Medical Branch 301 University Boulevard Galveston, TX 77555U.S.A.U.S.A.
CUNNINGHAM, Kathryn, A.c/o University of Texas Medical Branch 301 University Boulevard Galveston, TX 77555U.S.A.U.S.A.

Applicants

NameAddressCountryNationality
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM210 West 7th Street Austin, TX 78701U.S.A.U.S.A.

Documents

NameDate
202447082192-FORM-26 [04-12-2024(online)].pdf04/12/2024
202447082192-Proof of Right [05-11-2024(online)].pdf05/11/2024
202447082192-COMPLETE SPECIFICATION [28-10-2024(online)].pdf28/10/2024
202447082192-DECLARATION OF INVENTORSHIP (FORM 5) [28-10-2024(online)].pdf28/10/2024
202447082192-DRAWINGS [28-10-2024(online)].pdf28/10/2024
202447082192-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [28-10-2024(online)].pdf28/10/2024
202447082192-FORM 1 [28-10-2024(online)].pdf28/10/2024
202447082192-FORM 18 [28-10-2024(online)].pdf28/10/2024
202447082192-FORM FOR SMALL ENTITY(FORM-28) [28-10-2024(online)].pdf28/10/2024
202447082192-PRIORITY DOCUMENTS [28-10-2024(online)].pdf28/10/2024
202447082192-REQUEST FOR EXAMINATION (FORM-18) [28-10-2024(online)].pdf28/10/2024

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