PREPARATION OF A TRANSDERMAL PATCH OF PIOGLITAZONE AS AN ANTI DIABETIC AGENT

Abstract

Transdermal drug delivery systems have garnered considerable attention due to their non-invasive nature and ability to provide sustained drug release. This invention focused on the development and evaluation of transdermal patches loaded with Pioglitazone, a potent thiazolidinedione used in the treatment of diabetes mellitus. The transdermal patches were prepared using solvent casting process with a blend of biocompatible polymers and Pioglitazone. The formulated transdermal patches have tested for anti diabetic activity using male albino rats weighing about 200 g which were fasted for 18 hours before the experiment and found excellent anti-diabetic activity. The developed Pioglitazone loaded transdermal patches demonstrated promising characteristics and provides valuable insights into their potential as an effective and patient-friendly dosage form for the management of diabetes mellitus, offering improved therapeutic outcomes and enhanced patient compliance.

Specification

Description:Transdermal drug delivery systems have garnered considerable attention due to their non-invasive nature and ability to provide sustained drug release. This invention focused on the development and evaluation of transdermal patches loaded with Pioglitazone, a potent thiazolidinedione used in the treatment of diabetes mellitus. The transdermal patches were prepared using solvent casting process with a blend of biocompatible polymers and Pioglitazone. The formulated transdermal patches have tested for anti diabetic activity using male albino rats weighing about 200 g which were fasted for 18 hours before the experiment and found excellent anti-diabetic activity. The developed Pioglitazone loaded transdermal patches demonstrated promising characteristics and provides valuable insights into their potential as an effective and patient-friendly dosage form for the management of diabetes mellitus, offering improved therapeutic outcomes and enhanced patient compliance. , Claims:1. An improved method of preparation of transdermal patch loaded with Pioglitazone.
2. The method of preparation of transdermal patch as claimed in claim 1 comprising Pioglitazone and other pharmaceutical excipients for anti-inflammatory effect.
3. The method of preparation of transdermal patch as claimed in claim 1 comprising Pioglitazone and other pharmaceutical excipients for the treatment of diabetes mellitus.
4. The prepared transdermal patch composition as claimed in claim 1, wherein the process for the preparation of transdermal patch of Pioglitazone.
5. The method of fabricating the transdermal patch.

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