PHARMACEUTICAL DISPENSING AND MIXING DEVICE WITH REAL-TIME MONITORING AND RELATED METHODS

Abstract

ABSTRACT A pharmaceutical compounding device is designed to enhance accuracy and consistency in the compounding process. It integrates a spatula and a glass rod into a single compact device, combining dispensing and mixing functionalities. The spatula is configured for precise dispensing of active pharmaceutical ingredients (APIs), while the glass rod ensures uniform mixing with real-time parameter monitoring. A digital display provides real-time data on the weight of APIs and the temperature of materials, ensuring adherence to compounding protocols and preventing cross-contamination.

Specification

Description:PHARMACEUTICAL DISPENSING AND MIXING DEVICE WITH REAL-TIME MONITORING AND RELATED METHODS

TECHNICAL FIELD
[0001] Pharmaceutical dispensing and mixing device offers a solution for precise dispensing and mixing in pharmaceutical manufacturing, integrating real-time monitoring and enhanced sterility features.
BACKGROUND
[0002] The pharmaceutical industry is a critical sector that plays a vital role in healthcare by developing, producing, and distributing medications. One of the key processes in pharmaceutical manufacturing is compounding, which involves the precise mixing and dispensing of active pharmaceutical ingredients (APIs) to create medications tailored to specific patient needs. This process requires high levels of accuracy and sterility to ensure the safety and efficacy of the medications produced. Traditional tools used in compounding, such as spatulas and glass rods, often face challenges in maintaining precision and preventing cross-contamination, which can compromise the quality of the final product.

[0003] In recent years, there has been a growing demand for more advanced and reliable tools in pharmaceutical compounding to address these challenges. The need for precise measurement and control during the compounding process is paramount, as even minor deviations can lead to significant variations in medication potency and safety. Additionally, the industry is under constant pressure to improve efficiency and adhere to stringent regulatory standards, which necessitates the adoption of innovative solutions that can enhance the accuracy and consistency of compounding practices. As a result, there is a continuous push towards integrating technology and automation into pharmaceutical manufacturing to overcome the limitations of traditional methods and improve overall process reliability.
SUMMARY
[0004] In accordance with embodiments, a pharmaceutical compounding device is provided, comprising a spatula configured to dispense active pharmaceutical ingredients (APIs) using precise and controlled dispensing mechanisms. The spatula offers improved accuracy compared to conventional tools. Additionally, the device includes a glass rod configured to mix materials uniformly with enhanced mixing capabilities and real-time parameter monitoring and adjustment. A digital display is integrated with the spatula and the glass rod, providing real-time data on the weight of the APIs being dispensed by the spatula and the temperature of the materials being mixed by the glass rod, ensuring accuracy and consistency during the pharmaceutical compounding process.

[0005] In accordance with other embodiments, a method for pharmaceutical compounding is provided. This method involves integrating a spatula and a glass rod into a single compact device to combine dispensing and mixing functionalities. The method includes dispensing APIs using the spatula with precise and controlled dispensing mechanisms, offering improved accuracy over conventional tools. It also involves mixing materials uniformly using the glass rod with enhanced mixing capabilities and real-time parameter monitoring and adjustment. Real-time data on the weight of the APIs being dispensed and the temperature of the materials being mixed is provided by a digital display integrated with the spatula and the glass rod, ensuring accuracy and consistency during the pharmaceutical compounding process.

[0006] In yet other embodiments, the pharmaceutical compounding device includes a spatula with advanced measurement capabilities and sensors for accurate dispensing of the APIs. The glass rod enables adjustments for critical parameters during the mixing of materials. The digital display comprises a smart display screen that enhances precision and sterility during the pharmaceutical compounding process. The integration of the spatula and the glass rod into a single compact device enhances efficiency and reliability in pharmaceutical manufacturing by ensuring adherence to compounding protocols and preventing cross-contamination.

[0007] In further embodiments, the method for pharmaceutical compounding includes dispensing APIs using the spatula with advanced measurement capabilities and sensors for accurate dispensing. Mixing materials uniformly using the glass rod involves enabling adjustments for critical parameters during the mixing process. Providing real-time data on the weight of the APIs and the temperature of the materials involves utilizing a smart display screen integrated with the digital display to enhance precision and sterility during the pharmaceutical compounding process. Integrating the spatula and the glass rod into a single compact device enhances efficiency and reliability in pharmaceutical manufacturing by ensuring adherence to compounding protocols and preventing cross-contamination.
BRIEF DESCRIPTION OF THE DRAWINGS
[0008] FIG. 1 illustrates a multifunctional device enhancing pharmaceutical manufacturing efficiency by integrating dispensing and mixing functionalities.

DETAILED DESCRIPTION
[0009] The following detailed description illustrates embodiments of the present disclosure and ways in which they can be implemented. Although some modes of carrying out the present disclosure have been disclosed, those skilled in the art would recognise that other embodiments for carrying out or practising the present disclosure are also possible.

[0010] The description set forth below in connection with the appended drawings is intended as a description of certain embodiments of multi-temperature cabinet vaccine carrier box and is not intended to represent the only forms that may be developed or utilised. The description sets forth the various structures and/or functions in connection with the illustrated embodiments; however, it is to be understood that the disclosed embodiments are merely exemplary of the disclosure that may be embodied in various and alternative forms. The figures are not necessarily to scale; some features may be exaggerated or minimised to show details of particular components. Therefore, specific structural and functional details disclosed herein are not to be interpreted as limiting, but merely as a representative basis for teaching one skilled in the art to variously employ the present invention.

[0011] While the disclosure is susceptible to various modifications and alternative forms, specific embodiment thereof has been shown by way of example in the drawings and will be described in detail below. It should be understood, however, that it is not intended to limit the disclosure to the particular forms disclosed, but on the contrary, the disclosure is to cover all modifications, equivalents, and alternatives falling within the scope of the disclosure.
[0012] The terms "comprises", "comprising", "include(s)", or any other variations thereof, are intended to cover a non-exclusive inclusion, such that a setup, or system that comprises a list of components or steps does not include only those components or steps but may include other components or steps not expressly listed or inherent to such setup or system. In other words, one or more elements in a system or apparatus preceded by "comprises... a" does not, without more constraints, preclude the existence of other elements or additional elements in the system or apparatus.

[0013] In the following detailed description of the embodiments of the disclosure, reference is made to the accompanying drawings and which are shown by way of illustration-specific embodiments in which the disclosure may be practiced. These embodiments are described in sufficient detail to enable those skilled in the art to practice the disclosure, and it is to be understood that other embodiments may be utilized and that changes may be made without departing from the scope of the present disclosure. The following description is, therefore, not to be taken in a limiting sense.

[0014] The present disclosure will be described herein below with reference to the accompanying drawings. In the following description, well-known functions or constructions are not described in detail since they would obscure the description with unnecessary detail.

[0015] Referring to Fig. 1, the pharmaceutical dispensing and mixing device 100 is disclosed, in accordance with one embodiment of the present invention. The device integrates precise dispensing and uniform mixing functionalities within a single compact tool, specifically designed for pharmaceutical compounding. It comprises a spatula head 1102, spatula body 1104, smart display screen 1106, glass rod body 1108, glass rod end 1110, ambient parameter sensors 1112, and temperature display 1114.

[0016] Referring to Fig. 1, the pharmaceutical dispensing and mixing device 100 provides a multifunctional solution for pharmaceutical compounding by combining dispensing and mixing into a single device. It addresses common issues such as precision, sterility, and cross-contamination by integrating advanced measurement sensors and real-time monitoring capabilities. Key components include the spatula head 1102 for accurate API dispensing, a glass rod body 1108 for uniform mixing, and a smart display screen 106 that provides real-time feedback on the weight of apis and the temperature of materials, ensuring consistent quality in the compounding process.

[0017] The spatula head 1102 is configured for dispensing active pharmaceutical ingredients (APIs) with high precision. It includes integrated sensors that measure the exact quantity of material being dispensed, which addresses the common inaccuracies associated with traditional spatulas. This component is connected to the smart display screen 1106, where the dispensed weight is displayed in real-time, allowing the operator to monitor and adjust as necessary.

[0018] Referring to Fig. 1, the spatula body 1104 supports the spatula head and houses advanced measurement sensors for controlled dispensing. These sensors provide feedback to the digital display, ensuring stable positioning of the spatula head for accurate measurement during the compounding process. The stability of the spatula body 1104 enhances the precision of dispensing.

[0019] The smart display screen 1106, integrated with both the spatula and the glass rod, provides real-time monitoring of the weight of APIs dispensed and the temperature of materials mixed by the glass rod. This integration ensures continuous feedback, allowing users to make prompt adjustments, thereby enhancing accuracy and adherence to pharmaceutical standards.

[0020] In one embodiment, the glass rod body 1108 is designed for uniform mixing, featuring enhanced mixing capabilities that ensure even distribution of APIs and excipients. Integrated sensors monitor mixing consistency, which is critical for achieving homogeneity in pharmaceutical preparations. This component ensures that the final compound meets established quality standards for safety and efficacy.

[0021] The glass rod end 1110 completes the mixing process, providing a sterile interface to prevent contamination during compounding. Its design enables thorough mixing while maintaining sterility, reducing the likelihood of cross-contamination, which is essential in pharmaceutical applications.
[0022] Referring to Fig. 1, the ambient parameter sensors 1112 monitor environmental conditions, such as temperature and humidity, that can impact the stability and efficacy of APIs. By continuously tracking these parameters, the device ensures that the compounding process remains within optimal conditions necessary for producing high-quality compounds.

[0023] The temperature display 1114 provides real-time temperature data, which is essential for managing temperature-sensitive compounds. This secondary display enables operators to adjust as needed to maintain the correct temperature, preventing degradation of APIs or excipients, ensuring the stability and quality of the final product.

[0024] In other embodiment, the pharmaceutical dispensing and mixing device 100 operates through a systematic process flow that ensures accurate, efficient, and sterile compounding as shown in figure 2.

[0025] At step 100, the process begins by integrating the spatula and glass rod into a single compact device that combines dispensing and mixing functionalities. This setup reduces the need for multiple tools and streamlines the overall compounding process.

[0026] At step 102, in the dispensing phase, active pharmaceutical ingredients (APIs) are dispensed using the spatula with precise and controlled mechanisms. The integrated sensors in the spatula head ensure accurate dosing, addressing common inaccuracies associated with traditional spatulas.

[0027] At step 104, in the mixing phase, the glass rod is used to blend materials uniformly. Enhanced mixing capabilities and real-time parameter monitoring ensure consistent and homogeneous blending of APIs with other components, which is crucial for quality and safety in pharmaceutical preparations.

[0028] At step 106, real-time data on the weight of APIs dispensed and the temperature of materials being mixed is displayed via the digital screen. This continuous feedback allows operators to make necessary adjustments during the compounding process, enhancing accuracy and ensuring adherence to quality standards.

[0029] At step 108, the integration of the spatula and glass rod within a single compact device enhances the efficiency and reliability of pharmaceutical compounding. By consolidating these functionalities, the device minimizes cross-contamination risks and ensures that compounding protocols are followed precisely, contributing to higher standards in pharmaceutical manufacturing.

[0030] The pharmaceutical dispensing and mixing device 100, through its advanced components and streamlined process flow, addresses key issues in pharmaceutical compounding, providing a solution for precision, sterility, and operational efficiency in the preparation of active pharmaceutical ingredients.


















, Claims:We claim:
1. A pharmaceutical compounding device, comprising: a Spatula Head (102) configured to dispense active pharmaceutical ingredients (APIs) with precision and controlled accuracy;
a spatula body (104) housing sensors for monitoring dispensed material; a glass rod body (108) for uniform mixing of pharmaceutical materials;
a glass rod end (110) to maintain sterility during the mixing process;
a smart display screen (106) integrated to provide real-time data on api weight and material temperature, ensuring adherence to compounding protocols; and
ambient parameter sensors (112) and
temperature display (114) to monitor and control environmental conditions affecting the compounding process.

2. A method for pharmaceutical compounding, involving: dispensing APIs with the spatula head, utilizing advanced measurement sensors for precision; mixing materials using the glass rod body, with real-time monitoring for consistency; displaying weight and temperature data via a digital interface; and adjusting parameters dynamically to enhance accuracy, sterility, and protocol adherence during the compounding process.

3. The device of claim 1, wherein the Smart Display Screen (106) prevents manual intervention by enhancing sterility through real-time data display.

4. The device of claim 1, wherein Ambient Parameter Sensors (112) ensure optimal compounding conditions by monitoring environmental parameters and alerting users of any deviations.

5. The device of claim 2, wherein the Temperature Display (114) provides immediate feedback on mixing temperature, ensuring the quality and stability of temperature-sensitive APIs.

6. A process for pharmaceutical compounding using an integrated dispensing and mixing device, comprising:
integrating a spatula 102 and a glass rod 108 into a single compact device 100 to combine dispensing and mixing functionalities for efficient and controlled pharmaceutical compounding;
dispensing active pharmaceutical ingredients (APIs) using the spatula 102 with precise and controlled dispensing mechanisms, wherein the dispensed weight is monitored and displayed in real-time on a digital display 106 to ensure accurate dosing;
mixing materials uniformly using the glass rod 108 with enhanced mixing capabilities and real-time parameter monitoring, ensuring consistent homogeneity in the compound;
providing real-time data on the weight of APIs being dispensed and the temperature of the materials being mixed through the digital display 106, allowing for adjustments to maintain accuracy and adherence to quality standards; and
maintaining the efficiency and reliability of the compounding process by consolidating the dispensing and mixing functionalities in the single device 100, thereby minimizing cross-contamination risks and ensuring adherence to compounding protocols.

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