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NATURAL ANTI-FUNGAL CREAM AND RELATED METHODS

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NATURAL ANTI-FUNGAL CREAM AND RELATED METHODS

ORDINARY APPLICATION

Published

date

Filed on 6 November 2024

Abstract

ABSTRACT A natural anti-fungal cream is formulated with a blend of herbal ingredients such as neem extract, clove oil, ginger extract, eucalyptus oil, turmeric powder, and garlic extract, combined with a natural cream base free from synthetic preservatives. This topical formulation offers effective fungal control and provides natural skin benefits. The cream is designed for easy application and absorption, and is packaged in UV-resistant containers to prevent degradation. It demonstrates significant antifungal activity against pathogens like Candida albicans, Aspergillus niger, and Trichophyton rubrum, reducing symptoms such as redness, scaling, and itching. Suitable for health-conscious consumers, it minimizes the risk of side effects associated with synthetic chemicals and is recommended for twice-daily application over a period of at least two weeks. Reference fig 1

Patent Information

Application ID202411085190
Invention FieldCHEMICAL
Date of Application06/11/2024
Publication Number47/2024

Inventors

NameAddressCountryNationality
Yashna MehraChitkara College of Pharmacy, Chitkara University, Chandigarh-Patiala National Highway, Village- Jhansla, Tehsil- Rajpura, Distt. Patiala-140401(Punjab).IndiaIndia
Bhavesh DharmaniChitkara College of Pharmacy, Chitkara University, Chandigarh-Patiala National Highway, Village- Jhansla, Tehsil- Rajpura, Distt. Patiala-140401(Punjab).IndiaIndia
Rajwinder KaurChitkara College of Pharmacy, Chitkara University, Chandigarh-Patiala National Highway,Village- Jhansla, Tehsil- Rajpura, Distt. Patiala-140401(Punjab).IndiaIndia
Thakur Gurjeet SinghChitkara College of Pharmacy, Chitkara University, Chandigarh-Patiala National Highway, Village- Jhansla, Tehsil- Rajpura, Distt. Patiala-140401(Punjab).IndiaIndia

Applicants

NameAddressCountryNationality
Chitkara UniversityChitkara University, Chandigarh-Patiala National Highway, Village Jhansla, Rajpura, Punjab - 140401, IndiaIndiaIndia
Chitkara Innovation Incubator FoundationSCO: 160-161, Sector - 9c, Madhya Marg, Chandigarh- 160009, IndiaIndiaIndia

Specification

Description:TECHNICAL FIELD
[0001] The invention pertains to the development of a natural anti-fungal cream utilizing herbal ingredients for the treatment and prevention of fungal infections, offering a sustainable and holistic approach to healthcare.
BACKGROUND
[0002] Fungal infections are a common dermatological issue affecting millions of people worldwide. These infections, caused by various fungi, can lead to persistent and uncomfortable symptoms such as itching, redness, and scaling. Traditional treatments often involve the use of synthetic chemical-based antifungal agents, which, while effective, can sometimes result in adverse effects like skin irritation and allergic reactions. This has led to a growing demand for safer, more natural alternatives that can provide effective relief without the associated side effects.

[0003] In recent years, there has been an increasing interest in the use of herbal and plant-based ingredients in skincare and medical treatments. These natural ingredients are often perceived as safer and more environmentally friendly compared to their synthetic counterparts. The use of herbal extracts with known medicinal properties offers a promising avenue for developing effective treatments for fungal infections. However, creating a formulation that combines these ingredients in a way that maximizes their antifungal efficacy while ensuring user safety and product stability remains a significant challenge. The need for innovative solutions that address these challenges is critical in advancing natural healthcare options.
SUMMARY
[0004] In accordance with embodiments, a natural anti-fungal cream is provided, comprising a plurality of herbal ingredients including neem extract, clove oil, ginger extract, eucalyptus oil, turmeric powder, and garlic extract, blended into a natural cream base. This formulation provides effective fungal control through topical application, with the natural cream base being free from synthetic preservatives or stabilizers and comprising one or more of aloe vera gel, coconut oil, and shea butter.

[0005] In accordance with other embodiments, the natural anti-fungal cream is characterized by specific concentration ranges for each herbal ingredient: neem extract (5-15% by weight), clove oil (1-5% by weight), ginger extract (1-5% by weight), eucalyptus oil (0.5-2% by weight), turmeric powder (2-8% by weight), and garlic extract (1-5% by weight).

[0006] In yet other embodiments, the natural cream base facilitates easy application and absorption of the herbal ingredients by the skin, providing a holistic and synergistic effect against fungal infections while offering natural skin benefits.

[0007] In further embodiments, the cream is packaged in UV-resistant containers to protect it from degradation.

[0008] In accordance with additional embodiments, a method for treating or preventing fungal infections is provided, comprising applying the natural anti-fungal cream to an affected area. The cream includes the aforementioned herbal ingredients and natural cream base, blended to provide effective fungal control through topical formulation.

[0009] In other embodiments, the method demonstrates significant antifungal activity against fungal pathogens such as Candida albicans, Aspergillus niger, and Trichophyton rubrum, reducing infection symptoms including redness, scaling, and itching.

[0010] In further embodiments, the method is suitable for health-conscious consumers and those seeking natural alternatives to synthetic anti-fungal products, minimizing the risk of side effects associated with long-term use of synthetic chemicals, such as skin irritation and allergies.

[0011] In yet other embodiments, the method involves applying the natural anti-fungal cream twice daily for a period of at least two weeks.
[0012] In accordance with additional embodiments, the natural anti-fungal cream is targeted for healthcare and personal care markets.

[0013] In other embodiments, the cream is targeted for individuals seeking effective, natural treatments for managing fungal infections.
BRIEF DESCRIPTION OF THE DRAWINGS
[0014] FIG. 1 illustrates, in a flowchart, the application of a natural anti-fungal cream.
DETAILED DESCRIPTION
[0015] The development of natural anti-fungal creams represents a significant advancement in the field of topical treatments for fungal infections. These creams utilize a blend of herbal ingredients known for their medicinal properties, offering a natural alternative to synthetic chemical-based products. The technical formulation of these creams involves a combination of neem extract, clove oil, ginger extract, eucalyptus oil, turmeric powder, and garlic extract, each contributing to the cream's antifungal, anti-inflammatory, and soothing effects. The natural cream base, which includes aloe vera gel, coconut oil, and shea butter, facilitates the easy application and absorption of these herbal ingredients by the skin.

[0016] In an embodiment, this base is free from synthetic preservatives or stabilizers, aligning with the goal of providing a safe and non-toxic treatment option.

[0017] In another embodiment, the concentration ranges for the herbal ingredients are as follows: neem extract (5-15% by weight), clove oil (1-5% by weight), ginger extract (1-5% by weight), eucalyptus oil (0.5-2% by weight), turmeric powder (2-8% by weight), and garlic extract (1-5% by weight). These specific concentrations ensure the cream's efficacy and safety, providing a holistic and synergistic effect against fungal infections while offering skin benefits.

[0018] FIG. 1 is a flowchart illustrating a method for applying a natural anti-fungal cream to an affected area. The natural anti-fungal cream is applied to the affected area to provide fungal control through its topical formulation.

[0019] The cream demonstrates antifungal activity against common fungal pathogens, including Candida albicans, Aspergillus niger, and Trichophyton rubrum. This activity is evaluated through an in vitro anti-fungal assay, where the cream is tested for its ability to inhibit the growth of these pathogens.

[0020] The application of the cream also reduces infection symptoms, including redness, scaling, and itching, thereby offering relief to the user. The cream is suitable for consumers seeking natural alternatives to synthetic anti-fungal products, as it minimizes the risk of side effects associated with long-term use of synthetic chemicals, such as skin irritation and allergies.

[0021] The cream is applied twice daily for a period of at least two weeks, confirmed through clinical assessments to ensure its efficacy and safety on human skin. The natural anti-fungal cream is targeted for healthcare and personal care markets, reaching individuals seeking natural treatments for managing fungal infections.

[0022] The natural anti-fungal cream is packaged in UV-resistant containers to protect the cream from degradation. The packaging process involves placing the cream into these containers, which helps in maintaining the integrity and efficacy of the cream by shielding it from potential degradation caused by exposure to UV light. The UV-resistant containers serve as a barrier against environmental factors that could compromise the stability of the cream's active ingredients. This protective measure ensures that the cream retains its intended properties and effectiveness over time. The use of such containers is particularly beneficial in preserving the natural and herbal components of the cream, which are free from synthetic preservatives or stabilizers. The packaging strategy aligns with the overall goal of providing a natural and effective anti-fungal treatment that remains stable and potent throughout its shelf life.

Examples
[0023] Example 1: The table below provides the composition formula for each ingredient:

Ingredient Concentration Range (% by weight)
Neem Extract 5-15%
Clove Oil 1-5%
Ginger Extract 1-5%
Eucalyptus Oil 0.5-2%
Turmeric Powder 2-8%
Garlic Extract 1-5%
Natural Base (e.g., Aloe Vera Gel, Coconut Oil, Shea Butter) Balance (approx. 60-80%)


[0024] Example 2: Natural Anti-Fungal Cream
Ingredient Percentage by Weight (%)
Neem Extract 10%
Clove Oil 3%
Ginger Extract 3%
Eucalyptus Oil 1%
Turmeric Powder 5%
Garlic Extract 3%
Aloe Vera Gel 40%
Coconut Oil 25%
Shea Butter 10%

[0025] Example 3: Process
1. Fresh neem leaves, clove buds, ginger root, eucalyptus leaves, turmeric root, and garlic cloves are processed to create extracts and essential oils. Techniques such as cold pressing or aqueous extraction are used to preserve the active compounds in each ingredient.
2. The herbal extracts and oils are thoroughly mixed with the cream base (aloe vera gel, coconut oil, and shea butter) at controlled temperatures (30-40°C) to maintain the efficacy of the active ingredients.
3. The mixture is homogenized to ensure a uniform texture, allowing even distribution of the herbal ingredients for consistent application.
4. The cream is dispensed into UV-resistant containers to protect it from degradation, preserving the stability and potency of the active ingredients.

[0026] Table 4: demonstrate the anti-fungal activity of the natural cream against common fungal pathogens, as measured by the inhibition zone in millimeters (mm) through in vitro assays.
Fungal Pathogen Inhibition Zone (mm) Observation
Trichophyton rubrum 12-15 mm Significant inhibition of fungal growth
Candida albicans 15-20 mm Strong inhibition; effective anti-fungal activity
Aspergillus niger 18-22 mm Highest inhibition observed, indicating strong efficacy

[0027] The inhibition zones reflect the cream's effectiveness in suppressing fungal growth across different pathogens, demonstrating its broad-spectrum anti-fungal capability and suitability for managing various fungal infections.

Example 5: Synergistic Effects and Measured Efficacy of Ingredients
Table 5 :
Ingredient Combination Primary Function Inhibition Zone (mm) Inflammation Reduction (%) Observed Synergistic Effect
Neem Extract Anti-fungal, Anti-inflammatory 10 mm 20% Inhibits fungal growth and reduces inflammation, forming a strong anti-fungal base.
Clove Oil + Neem Extract Potent Anti-fungal combination 18 mm 30% Clove enhances neem's anti-fungal activity, leading to an increased inhibition zone.
Neem + Clove + Garlic Extract Enhanced Anti-fungal, Anti-microbial 22 mm 40% Synergistic combination that maximizes fungal inhibition and provides broad-spectrum anti-microbial effects.
Ginger Extract + Turmeric Powder Anti-inflammatory, Skin Healing 15 mm 35% Combined anti-inflammatory action significantly reduces redness and promotes skin healing.
Eucalyptus Oil + Ginger + Clove Antiseptic, Cooling, Anti-fungal 17 mm 30% Eucalyptus provides cooling relief, while ginger and clove enhance fungal control and skin comfort.
Neem + Clove + Ginger + Turmeric Comprehensive Anti-fungal, Anti-inflammatory 25 mm 50% Synergistic combination maximizes anti-fungal activity and reduces inflammation, leading to faster recovery.
Aloe Vera Gel + Coconut Oil + Shea Butter Hydrating, Soothing Base N/A 45% Provides deep hydration and improves absorption, enhancing the efficacy of active anti-fungal ingredients.

[0028] The synergistic combination of ingredients in the natural anti-fungal cream significantly enhances its efficacy and skin benefits. When neem, clove, and garlic are combined, the anti-fungal activity is amplified, as evidenced by an increase in the inhibition zone from 10 mm (observed with neem alone) to 22 mm, showcasing a marked improvement in fungal inhibition through their combined effects. Furthermore, the anti-inflammatory benefits are considerably strengthened with the addition of clove, ginger, and turmeric alongside neem, achieving a 50% reduction in skin inflammation compared to the 20% reduction observed with neem alone. This synergy highlights how these ingredients work together to produce a stronger, more effective anti-inflammatory response. Additionally, the cream's base, composed of aloe vera, coconut oil, and shea butter, delivers a 45% improvement in skin hydration and reduces irritation, creating a protective layer that helps retain the active ingredients on the skin longer. This hydration boost not only aids in soothing irritated skin but also enhances the absorption and effectiveness of the active anti-fungal compounds, promoting faster recovery and a more comprehensive treatment experience.
, Claims:CLAIMS
We claim:
1. A natural anti-fungal cream comprising:
a plurality of herbal ingredients including neem extract, clove oil, ginger extract, eucalyptus oil, turmeric powder, and garlic extract; and
a natural cream base;
wherein the herbal ingredients are blended into the natural cream base to provide effective fungal control through a topical formulation, and wherein the natural cream base is free from synthetic preservatives or stabilizers and comprises one or more of aloe vera gel, coconut oil, and shea butter.

2. The natural anti-fungal cream as claimed in claim 1, wherein:
the neem extract is present in a concentration range of 5-15% by weight;
the clove oil is present in a concentration range of 1-5% by weight;
the ginger extract is present in a concentration range of 1-5% by weight;
the eucalyptus oil is present in a concentration range of 0.5-2% by weight;
the turmeric powder is present in a concentration range of 2-8% by weight; and
the garlic extract is present in a concentration range of 1-5% by weight.

3. The natural anti-fungal cream as claimed in claim 1, wherein the natural cream base facilitates easy application and absorption of the herbal ingredients by the skin, and wherein the herbal ingredients provide a holistic and synergistic effect against fungal infections while offering natural skin benefits.

4. The natural anti-fungal cream as claimed in claim 1, wherein the cream is packaged in UV-resistant containers to protect the cream from degradation.

5. A method for treating or preventing fungal infections, the method comprising:
applying a natural anti-fungal cream to an affected area, wherein the natural anti-fungal cream comprises:
a plurality of herbal ingredients including neem extract, clove oil, ginger extract, eucalyptus oil, turmeric powder, and garlic extract; and
a natural cream base;
wherein the herbal ingredients are blended into the natural cream base to provide effective fungal control through a topical formulation.

6. The method as claimed in claim 5, wherein the natural anti-fungal cream demonstrates significant antifungal activity against one or more fungal pathogens selected from the group consisting of Candida albicans, Aspergillus niger, and Trichophyton rubrum, and wherein the natural anti-fungal cream reduces infection symptoms including redness, scaling, and itching.

7. The method as claimed in claim 5, wherein the natural anti-fungal cream is suitable for health-conscious consumers and those seeking natural alternatives to synthetic anti-fungal products, and wherein the natural anti-fungal cream minimizes the risk of side effects associated with long-term use of synthetic anti-fungal chemicals, such as skin irritation and allergies.

8. The method as claimed in claim 5, wherein the natural anti-fungal cream is applied twice daily for a period of at least two weeks.

9. The method as claimed in claim 5, wherein the natural anti-fungal cream is targeted for healthcare and personal care markets.

10. The method as claimed in claim 5, wherein the natural anti-fungal cream is targeted for individuals seeking effective, natural treatments for managing fungal infections.

Documents

NameDate
202411085190-COMPLETE SPECIFICATION [06-11-2024(online)].pdf06/11/2024
202411085190-DECLARATION OF INVENTORSHIP (FORM 5) [06-11-2024(online)].pdf06/11/2024
202411085190-DRAWINGS [06-11-2024(online)].pdf06/11/2024
202411085190-EDUCATIONAL INSTITUTION(S) [06-11-2024(online)].pdf06/11/2024
202411085190-EVIDENCE FOR REGISTRATION UNDER SSI [06-11-2024(online)].pdf06/11/2024
202411085190-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [06-11-2024(online)].pdf06/11/2024
202411085190-FIGURE OF ABSTRACT [06-11-2024(online)].pdf06/11/2024
202411085190-FORM 1 [06-11-2024(online)].pdf06/11/2024
202411085190-FORM FOR SMALL ENTITY(FORM-28) [06-11-2024(online)].pdf06/11/2024
202411085190-FORM FOR STARTUP [06-11-2024(online)].pdf06/11/2024
202411085190-FORM-9 [06-11-2024(online)].pdf06/11/2024
202411085190-POWER OF AUTHORITY [06-11-2024(online)].pdf06/11/2024
202411085190-REQUEST FOR EARLY PUBLICATION(FORM-9) [06-11-2024(online)].pdf06/11/2024

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