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MULTICOMPONENT SYSTEMS FOR SITE-SPECIFIC GENOME MODIFICATIONS
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Abstract
Information
Inventors
Applicants
Specification
Documents
PCT NATIONAL PHASE APPLICATION
Published
Filed on 25 November 2024
Abstract
The invention includes systems, compositions, and. methods for the making of modular gene editing through reverse transcriptase related processes. Systems and methods that use modified nucleotides and peptides are specifically provided. Transgene introduction into eukaryotic genomes offers vast opportunities to improve, correct and/or alter genetic expression, and concomitantly serve to treat or ameliorate disease symptoms. Successful transgene insertion would allow for rescue from loss-of-function mutations, inhibition of gain-of-function mutations, the exogenous control of RNA and/or protein expression, the introduction of isoform expression specificity, engineered gene and protein expression, and other useful outcomes.
Patent Information
Application ID | 202437091617 |
Invention Field | BIO-CHEMISTRY |
Date of Application | 25/11/2024 |
Publication Number | 48/2024 |
Inventors
Name | Address | Country | Nationality |
---|---|---|---|
COLLINS, Kathleen | 2150 Shattuck Ave., Suite 510 Berkeley, California 94704 | U.S.A. | U.S.A. |
ZHANG, Ziaozhu | 2150 Shattuck Ave., Suite 510 Berkeley, California 94704 | U.S.A. | U.S.A. |
VAN TREECK, Briana | 2150 Shattuck Ave., Suite 510 Berkeley, California 94704 | U.S.A. | U.S.A. |
UPTON, Heather E. | 2150 Shattuck Ave., Suite 510 Berkeley, California 94704 | U.S.A. | U.S.A. |
PALM, Sarah | 2150 Shattuck Ave., Suite 510 Berkeley, California 94704 | U.S.A. | U.S.A. |
MCINTYRE, Jeremy | 2150 Shattuck Ave., Suite 510 Berkeley, California 94704 | U.S.A. | U.S.A. |
Applicants
Name | Address | Country | Nationality |
---|---|---|---|
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 1111 Franklin Street, 12th Floor Oakland, California 94607 | U.S.A. | U.S.A. |
Documents
Name | Date |
---|---|
202437091617-Proof of Right [27-11-2024(online)].pdf | 27/11/2024 |
202437091617-DECLARATION OF INVENTORSHIP (FORM 5) [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-DRAWINGS [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-EVIDENCE FOR REGISTRATION UNDER SSI(FORM-28) [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-FORM 1 [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-FORM 18 [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-FORM FOR SMALL ENTITY(FORM-28) [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-POWER OF AUTHORITY [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-PRIORITY DOCUMENTS [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-REQUEST FOR EXAMINATION (FORM-18) [25-11-2024(online)].pdf | 25/11/2024 |
202437091617-Sequence Listing in PDF [25-11-2024(online)].pdf | 25/11/2024 |
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