MEDICAL PLASTERING COMPOSITE WITH ANTI-BACTERIAL EFFECT AND METHOD OF PREPARATION THEREOF

Abstract

ABSTRACT MEDICAL PLASTERING COMPOSITE WITH ANTI-BACTERIAL EFFECT AND METHOD OF PREPARATION THEREOF The present invention relates to a medical plastering composite with anti-bacterial effect and method of preparation thereof. The method of preparation of the medical plastering composite comprises of milling jade, tourmaline, graphene and bian stone through dry milling machine; pulverizing via an ultrasonic pulverizer for obtaining micronized jade, tourmaline, graphene and bian stone particles; coating micronized jade with zinc oxide nanoparticles using thermal evaporation deposition; and combining coated jade with the micronized tourmaline, graphene and bian stone using a planetary ball mixer for homogeneity resulting in medical plastering composite. The lightweight medical plastering composite with anti-bacterial effect described in this patent represents a significant advancement in wound care technology, offering a novel solution to the longstanding challenges faced by traditional plaster materials. By incorporating cutting-edge materials and technologies, this invention aims to improve patient outcomes and provide a more effective, comfortable, and reliable option for medical plastering applications.

Specification

Description:MEDICAL PLASTERING COMPOSITE WITH ANTI-BACTERIAL EFFECT AND METHOD OF PREPARATION THEREOF
FIELD OF THE INVENTION
[0001] The present invention in general relates to medical plasters. More particularly, the present invention relates to a medical plastering composite with anti-bacterial effect and method of preparation thereof.
BACKGROUND
[0002] Medical plasters and bandages are essential tools in wound management, providing protection and support to injured or compromised skin. Traditional plastering materials, such as gauze and adhesive bandages, have been widely used for decades. However, these conventional products face several limitations that impact their effectiveness and patient comfort:
• Weight and Rigidity: Traditional plasters can be bulky and rigid, which may restrict movement and cause discomfort, especially when applied to areas of the body that experience frequent motion. The added weight can also be burdensome, particularly for long-term applications or for patients with mobility issues.
• Limited Flexibility: Many existing plasters do not conform well to the contours of the body, leading to poor adhesion and potential gaps where bacteria and contaminants can enter. This lack of flexibility can result in reduced effectiveness in protecting the wound.
• Infection Risk: One of the primary concerns in wound care is preventing bacterial infection. Conventional plasters may not provide adequate antimicrobial protection, making them less effective in preventing infection, particularly in environments where bacteria are prevalent.
• Breathability: Many traditional plasters do not allow for sufficient airflow to the wound area, which can create a moist environment conducive to bacterial growth and may prolong the healing process.
• Patient Comfort: The comfort of patients wearing medical plasters is a significant consideration. Materials that are too rigid, heavy, or adhesive can cause skin irritation and discomfort, impacting the patient's overall experience and adherence to treatment.
[0003] In recent years, there has been a growing demand for advanced plastering materials that address these issues by incorporating modern materials and technologies. Innovations in polymer science and antimicrobial treatments have provided opportunities to develop new types of medical plasters that offer improved performance in several key areas. Advances in polymer technology have led to the development of lightweight materials that offer the same or better performance than traditional plasters while reducing weight and enhancing comfort.
[0004] Prior art studies and patents have explored medical analgesic plasters. For example, Patent application number US11116994B2 discloses a medical patch with active ingredients. The patch contains at least one filler and at least one active ingredient, wherein the local distribution of the active ingredient or ingredients within the patch takes place dependent on the morphology, anatomy and physiology of the lesion to be treated.
[0005] These prior works highlight the potential of advancements in medical plastering materials. However, they have a tendency to enhance microcirculation and promote the discharge of organic matter through sweat. This can foster bacterial and microbial growth. They also struggle to manage inflammation effectively, often requiring additional anti-inflammatory agents.
[0006] Despite some advancements, these disclosures face limitations as they fail to provide a comprehensive solution for a lightweight, flexible, breathable, and anti-bacterial medical analgesic plaster. To boost the effectiveness of medical plastering composite, materials such as pearl powder, chitin, and diamonds have been added.
[0007] For example, patent application CN105821503A discloses Pearl antifungal fiber containing multiple amino acids and microelement and preparing method thereof. However, the high cost of these additives raises the overall expense of the medical plastering composite.
[0008] The present invention addresses this need by providing a medical plastering composite that not only meets but exceeds current standards in terms of performance and patient comfort. The lightweight medical plastering composite with anti-bacterial effect described in this patent represents a significant advancement in wound care technology, offering a novel solution to the longstanding challenges faced by traditional plaster materials. By incorporating cutting-edge materials and technologies, this invention aims to improve patient outcomes and provide a more effective, comfortable, and reliable option for medical plastering applications.
OBJECTS OF THE INVENTION
[0009] The object of the present invention is to provide a medical plastering composite with anti-bacterial effect and method of preparation thereof.
[0010] It is another object of the present invention to develop a comprehensive solution that combines all attributes being lightweight, anti-inflammatory and anti-bacterial into a single, effective plastering composite.
SUMMARY OF THE INVENTION
[0011] In an aspect, the present invention discloses a method for preparing a medical plastering composite. The method comprises milling jade, tourmaline, graphene and bian stone through dry milling machine for a duration of 2 to 6 hrs; pulverizing via an ultrasonic pulverizer for a cycle of 5 times each for a duration of 3-5 seconds for obtaining micronized jade, tourmaline, graphene and bian stone particles; coating micronized jade with zinc oxide nanoparticles using thermal evaporation deposition at a temperature of 350-550 ºC for uniform nanocoating; and combining coated jade with the micronized tourmaline, graphene and bian stone using a planetary ball mixer for homogeneity resulting in medical plastering composite.
[0012] In another aspect, the combining coated jade with the micronized tourmaline, graphene and bian stone in a vacuum environment by a vaccum pump at a pressure range of 105-10−11 Pa.
[0013] In another aspect, the present invention also discloses a medical plastering composite with anti-bacterial effect. The medical plastering composite comprises of jade in an amount of 10-20% by weight; tourmaline in an amount of 25-45% by weight; graphene in an amount of 15-30% by weight; zinc oxide in an amount of 8-20% by weight; and bian stone in an amount of 5-10% by weight.
[0014] In yet another aspect, the components are preferably jade in an amount of 18-20% by weight, tourmaline in an amount of 35-45% by weight, graphene in an amount of 20-30% by weight, zinc oxide in an amount of 12-20% by weight, and bian stone in an amount of 5-7% by weight.
[0015] In another aspect, the median particle size (D50) of each of the jade, tourmaline, graphene, zinc oxide, and bian stone is not greater than 0.4 µm.
[0016] In another aspect, the jade has a density in a range of 2.2-3.4 g/cm3, the tourmaline has a density in a range of 3.2-3.4 g/cm3, the graphene has a density in a range of 2.0-2.2 g/cm3, and the bian stone has a density in a range of 2.8-3.4 g/cm3.
[0017] In another aspect, the jade, tourmaline, and graphene having a purity of at least 98 wt.%.
[0018] In yet another aspect, the jade with zinc oxide nanoparticles having a mass ratio of zinc oxide to jade in a range of 4:1 to 4:3.
[0019] Overall, the invention provides a sophisticated wastewater treatment system that leverages IoT technology to optimize treatment processes, reduce operational costs, and ensure environmentally friendly discharge or reuse of treated water. The system's innovative design and IoT integration enable precise management and control of water treatment, offering an effective solution for wastewater purification and resource conservation.
BRIEF DESCRIPTION OF THE DRAWING
[0020] The accompanying drawing is included to provide a further understanding of the present disclosure and is incorporated in and constitutes a part of this specification. The drawing illustrates exemplary embodiment of the present disclosure and, together with the, serve to explain the principles of the present disclosure.
[0021] Figure 1 illustrates a flowchart of method for preparing a medical plastering composite.
DETAILED DESCRIPTION
[0022] The following description includes the preferred best mode of one embodiment of the present invention. It will be clear from this description of the invention that the invention is not limited to these illustrated embodiments but that the invention also includes a variety of modifications and embodiments thereto. Therefore, the present description should be seen as illustrative and not limiting. While the invention is susceptible to various modifications and alternative constructions, it should be understood, that there is no intention to limit the invention to the specific form disclosed, but, on the contrary, the invention is to cover all modifications, alternative constructions, and equivalents.
[0023] The present invention provides a medical plastering composite with anti-bacterial effect. The medical plastering composite comprises of jade; tourmaline; graphene; zinc oxide; and bian stone. All the components and chemicals are purchased from the market. The jade, tourmaline, graphene and bian stone is having a purity of at least 98 wt.%.
[0024] In an embodiment of the invention, the jade is in an amount of 10-20% by weight; tourmaline is in an amount of 25-45% by weight; graphene is in an amount of 15-30% by weight; zinc oxide is in an amount of 8-20% by weight; and bian stone is in an amount of 5-10% by weight.
Method of preparation:
[0025] Figure 1 illustrates a flowchart of method for preparing a medical plastering composite. The milling of jade, tourmaline, graphene and bian stone is done through dry milling machine for a duration of 2 to 6 hrs. The milled mixture is pulverized via an ultrasonic pulverizer for a cycle of 5 times each for a duration of 3-5 seconds for obtaining micronized jade, tourmaline, graphene and bian stone particles. The micronized jade is coated with zinc oxide nanoparticles using thermal evaporation deposition at a temperature of 350-550 ºC for uniform nanocoating. The micronized jade is coated with zinc oxide nanoparticles having a mass ratio of zinc oxide to jade in a range of 4:1 to 4:3. The coated jade is combined with the micronized tourmaline, graphene and bian stone using a planetary ball mixer for homogeneity resulting in medical plastering composite. The combining of coated jade with the micronized tourmaline, graphene and bian stone is done in a vacuum environment by a vacuum pump at a pressure range of 105-10−11 Pa.
[0026] The prepared medical plastering composite can further be formed as a cast by traditional mold casting method. It can be combined with plaster of paris to form a plaster mold.
[0027] Table 1 sets forth the sequence of steps involved in the preparation of the medical plastering composite with antibacterial properties, based on specific processing parameters. The plurality of steps includes dry milling, pulverization, nanoparticle coating, and mixing, thereby ensuring that the composite achieves the intended antibacterial effect.
Table 1: Method for Preparing the Medical Plastering Composite

Process Step Parameters
Dry Milling Duration: 2 to 6 hours
Pulverization 5 cycles, each lasting 3-5 seconds
Nanoparticle Coating Temperature: 350-550ºC
Mixing Vacuum pressure: 10⁵-10⁻¹¹ Pa
[0028] Table 2 illustrates the process of coating jade with zinc oxide nanoparticles. The coating process involves the application of zinc oxide nanoparticles to micronized jade using thermal evaporation. The temperature during this process is maintained between approximately 350°C and 550°C to ensure effective nanocoating.
Table 2: Jade Coating with Zinc Oxide Nanoparticles

Coating Process Parameters
Zinc Oxide Coating Temperature: 350-550ºC
Zinc Oxide to Jade Ratio Zinc oxide to jade ratio: 4:1 to 4:3
Effect of Coating Uniform coating across jade particles
[0029] In an embodiment of the invention, the components are preferably jade in an amount of 18-20% by weight, tourmaline in an amount of 35-45% by weight, graphene in an amount of 20-30% by weight, zinc oxide in an amount of 12-20% by weight, and bian stone in an amount of 5-7% by weight. The median particle size (D50) of each of the jade, tourmaline, graphene, zinc oxide, and bian stone is not greater than 0.4 µm. In the disclosed composition, the jade has a density in a range of 2.2-3.4 g/cm3, the tourmaline has a density in a range of 3.2-3.4 g/cm3, the graphene has a density in a range of 2.0-2.2 g/cm3, and the bian stone has a density in a range of 2.8-3.4 g/cm3.
[0030] Jade is a crystal which is used due to its high-intensity electron activity. The electron diffraction within jade releases energy that can affect the body's bioelectricity, stimulate the endocrine system, and support metabolic regulation. Tourmaline demonstrates a distinctive photoelectric effect and creates an electromagnetic field during its cutting, grinding, and polishing. These properties allow tourmaline to resonate with the human body, facilitating more harmonious bodily functions. Tourmaline's surface activity can inhibit the growth of bacteria and microorganisms, which helps in maintaining a sterile environment and preventing infections in wounds.
[0031] Graphene is approximately 100 times stronger than steel, yet incredibly lightweight. When incorporated into medical plaster composition, graphene can significantly enhance the strength and durability of the plaster, making it more resistant to tearing and wear while maintaining a thin and flexible profile. The use of Bian stone in medical plasters helps stimulate blood flow to the affected area. Improved circulation supports nutrient delivery and waste removal, which are essential for the healing process and overall tissue health.
[0032] Table 3 illustrates the prepared sample medical plastering composites as per the disclosed percentages of components.
Table 3: Sample medical plastering composites

Component Composite C1 (%) Composite C2 (%) Composite C3 (%)
Jade 18 20 18
Tourmaline 45 38 42
Graphene 25 22 23
Zinc Oxide 12 15 10
Bian Stone 10 5 7

[0033] Example-1
Weight of composite material: 500mg
Quantity of Jade -90 mg Density of Jade -2.8 g/cm3
Quantity of Tourmaline -225 mg Density of Tourmaline -3.2 g/cm3
Quantity of Graphene -125 mg Density of Graphene -2.2 g/cm3
Quantity of Bian stone -50 mg Density of Bian stone -3 g/cm3
Quantity of Zinc oxide -60 mg

[0034] Example-2
Weight of composite material: 100mg
Quantity of Jade -20 mg Density of Jade -3.4 g/cm3
Quantity of Tourmaline -38 mg Density of Tourmaline -3.4 g/cm3
Quantity of Graphene -22 mg Density of Graphene -2.0 g/cm3
Quantity of Bian stone -15 mg Density of Bian stone -3.2 g/cm3
Quantity of Zinc oxide -5 mg

[0035] The anti-microbial and bacteriostatic properties of the sample composites were tested. All the sample composites exhibited strong antibacterial effect due to the synergistic combination of jade, tourmaline, graphene, zinc oxide nanoparticles, and bian stone. This composition is particularly effective against well-known infection causing pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli making it highly beneficial for promoting wound healing and minimizing infection risk. Table 4 illustrates the results of the antibacterial effect of the sample medical plastering composites. The Antibacterial efficiency is tested by measuring Zone of Inhibition (ZoI) for composites.
Table 4: Antibacterial effect of Sample medical plastering composite

Composite Antibacterial efficiency (ZoI in mm)
Pseudomonas aeruginosa Staphylococcus aureus Escherichia coli
C1 7.1± 0.3 18.4± 0.5 18.1± 0.2
C2 7.4± 0.4 19.7 ± 0.3 18.8 ± 0.3
C3 6.9± 0.2 17.2 ± 0.4 17.8 ± 0.4

[0036] Advantages of the invented medical plastering composite with anti-bacterial effect and method of preparation:
• Lightweight Materials: The components are lightweight materials that offer better performance than traditional plasters while reducing weight and enhancing comfort.
• Enhanced Flexibility: The engineered composite provides greater flexibility and conformability, allowing the plaster to move with the body and maintain a secure fit.
• Anti-Bacterial Properties: The integration of anti-bacterial agents into the plaster matrix helps to prevent bacterial growth and reduce the risk of infection.
• Improved Breathability: New materials that enhance breathability help to maintain a dry and clean wound environment, promoting faster healing and reducing the risk of complications.
• Patient-Centric Design: Emphasis on patient comfort has led to the development of softer, more conformable material that minimize skin irritation and enhance user experience.
[0037] Although the present invention has been particularly described with reference to implementations discussed above, various changes, modifications and Substitutes are can be made. Accordingly, it will be appreciated that in numerous instances some features of the invention can be employed without a corresponding use of other features. Further, variations can be made in the number and arrangement of components illustrated in the figures discussed above.
, Claims:I/We Claim:
1. A method for preparing a medical plastering composite, comprising the steps of:
milling jade, tourmaline, graphene and bian stone through dry milling machine for a duration of 2 to 6 hrs;
pulverizing via an ultrasonic pulverizer for a cycle of 5 times each for a duration of 3-5 seconds for obtaining micronized jade, tourmaline, graphene and bian stone particles;
coating micronized jade with zinc oxide nanoparticles using thermal evaporation deposition at a temperature of 350-550 ºC for uniform nanocoating; and
combining coated jade with the micronized tourmaline, graphene and bian stone using a planetary ball mixer for homogeneity resulting in medical plastering composite.
2. The method as claimed in claim 1, wherein the processing jade, tourmaline, graphene, bian stone and coating with zinc oxide nanoparticles includes jade in an amount of 10-20% by weight, tourmaline in an amount of 25-45% by weight, graphene in an amount of 15-30% by weight, zinc oxide in an amount of 8-20% by weight, and bian stone in an amount of 5-10% by weight.
3. The method as claimed in claim 1, wherein the coating micronized jade with zinc oxide nanoparticles having a mass ratio of zinc oxide to jade in a range of 4:1 to 4:3.
4. The method as claimed in claim 1, wherein the combining coated jade with the micronized tourmaline, graphene and bian stone in a vacuum environment by a vaccum pump at a pressure range of 105-10−11 Pa.
5. A medical plastering composite with anti-bacterial effect, comprising of:
jade in an amount of 10-20% by weight;
tourmaline in an amount of 25-45% by weight;
graphene in an amount of 15-30% by weight;
zinc oxide in an amount of 8-20% by weight; and
bian stone in an amount of 5-10% by weight.
6. The medical plastering composite as claimed in claim 5, wherein the components are preferably jade in an amount of 18-20% by weight, tourmaline in an amount of 35-45% by weight, graphene in an amount of 20-30% by weight, zinc oxide in an amount of 12-20% by weight, and bian stone in an amount of 5-7% by weight.
7. The medical plastering composite as claimed in claim 5, wherein the median particle size (D50) of each of the jade, tourmaline, graphene, zinc oxide, and bian stone is not greater than 0.4 µm.
8. The medical plastering composite as claimed in claim 5, wherein the jade has a density in a range of 2.2-3.4 g/cm3, the tourmaline has a density in a range of 3.2-3.4 g/cm3, the graphene has a density in a range of 2.0-2.2 g/cm3, and the bian stone has a density in a range of 2.8-3.4 g/cm3.
9. The medical plastering composite as claimed in claim 5, wherein the jade, tourmaline, graphene, and bian stone having a purity of at least 98 wt.%.
10. The medical plastering composite as claimed in claim 5, wherein the jade with zinc oxide nanoparticles having a mass ratio of zinc oxide to jade in a range of 4:1 to 4:3.

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