HIGH-THROUGHPUT MICROFLUIDIC SYSTEM FOR ORGANIC COMPOUND SYNTHESIS USING CLICK CHEMISTRY

Abstract

The present invention discloses a high-throughput microfluidic system for the efficient synthesis of organic compounds using click chemistry. The system integrates a network of precisely engineered microchannels, automated reagent delivery systems, and micro-mixers to ensure optimal reagent interaction. Temperature-controlled reaction chambers with integrated sensors enable precise reaction optimization, while a real-time monitoring module employs optical sensors for tracking reaction progress. A feedback control system dynamically adjusts reaction parameters, enhancing efficiency and yield. The system's modular design allows flexibility for diverse reactions, including azide-alkyne cycloaddition and thiol-ene coupling. Additionally, an intuitive software interface automates parameter control, data logging, and process optimization through machine learning. The invention reduces resource consumption, minimizes reaction times, and ensures scalability for industrial and research applications. It provides an env

Specification

Description:[001] The present invention relates to the field of chemical synthesis, particularly to methods and systems for the high-throughput synthesis of organic compounds. More specifically, the invention pertains to a microfluidic platform utilizing click chemistry techniques to enable efficient, rapid, and scalable production of diverse organic molecules. This invention finds applications in pharmaceuticals, materials science, and other chemical industries requiring precise and automated synthesis of complex compounds.
BACKGROUND OF THE INVENTION
[002] Background description includes information that may be useful in understanding the present disclosure. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed disclosure, or that any publication specifically or implicitly referenced is prior art.
[003] Chemical synthesis is a cornerstone of modern science and industry, enabling the development of pharmaceuticals, materials, and biologically active molecule , Claims:1. A high-throughput microfluidic system for organic compound synthesis using click chemistry, comprising:
a) a microfluidic platform with interconnected microchannels configured to facilitate the controlled flow and mixing of reagents;
b) a reagent delivery system employing automated pumps for precise control of reagent flow rates and volumes;
c) integrated micro-mixers designed to enhance reagent mixing through chaotic advection or diffusion-based mechanisms;
d) temperature-controlled reaction chambers equipped with localized heating elements and sensors for precise temperature regulation during chemical reactions;
e) a real-time monitoring module comprising optical sensors for analyzing reaction progress through absorbance or fluorescence measurements;
f) a feedback control system that dynamically adjusts reaction parameters based on real-time monitoring data to optimize reaction efficiency and yield; and
g) a software interface for automated control, parameter adjustment, and real-time visualization of re

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