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CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS
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CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS
PCT NATIONAL PHASE APPLICATION
Published
Filed on 6 November 2024
Abstract
The present inventors found a cyclic compound that selectively inhibits KRAS. The present inventors also found that the cyclic compound interacts with a KRAS-specific amino acid residue.
Patent Information
| Application ID | 202447084925 |
| Invention Field | CHEMICAL |
| Date of Application | 06/11/2024 |
| Publication Number | 47/2024 |
Inventors
| Name | Address | Country | Nationality |
|---|---|---|---|
| KAWADA Hatsuo | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 200, Kajiwara, Kamakura-shi, Kanagawa 2478530 | Japan | Japan |
| TAKANO Koji | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 200, Kajiwara, Kamakura-shi, Kanagawa 2478530 | Japan | Japan |
| KOTAKE Tomoya | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 135, Komakado 1-chome, Gotemba-shi, Shizuoka 4128513 | Japan | Japan |
| KAGE Mirai | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 135, Komakado 1-chome, Gotemba-shi, Shizuoka 4128513 | Japan | Japan |
| HASHIMOTO Satoshi | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 135, Komakado 1-chome, Gotemba-shi, Shizuoka 4128513 | Japan | Japan |
| TAMIYA Minoru | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 200, Kajiwara, Kamakura-shi, Kanagawa 2478530 | Japan | Japan |
| WAKAMIYA Yuma | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 200, Kajiwara, Kamakura-shi, Kanagawa 2478530 | Japan | Japan |
| HAYASHI Ryuji | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 200, Kajiwara, Kamakura-shi, Kanagawa 2478530 | Japan | Japan |
| MORITA Yuya | c/o CHUGAI SEIYAKU KABUSHIKI KAISHA, 200, Kajiwara, Kamakura-shi, Kanagawa 2478530 | Japan | Japan |
Applicants
| Name | Address | Country | Nationality |
|---|---|---|---|
| CHUGAI SEIYAKU KABUSHIKI KAISHA | 5-1, Ukima 5-chome, Kita-ku, Tokyo 1158543 | Japan | Japan |
Documents
| Name | Date |
|---|---|
| 202447084925-FORM-26 [07-11-2024(online)].pdf | 07/11/2024 |
| 202447084925-COMPLETE SPECIFICATION [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-DECLARATION OF INVENTORSHIP (FORM 5) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-FORM 1 [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-FORM 18 [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-PRIORITY DOCUMENTS [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-PROOF OF RIGHT [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084925-REQUEST FOR EXAMINATION (FORM-18) [06-11-2024(online)].pdf | 06/11/2024 |
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