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COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACTINOMYCETIA INFECTIONS
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COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACTINOMYCETIA INFECTIONS
PCT NATIONAL PHASE APPLICATION
Published
Filed on 6 November 2024
Abstract
The present disclosure features compositions and methods for the treatment of actinomycetia (e.g., corynebacteriales) infections, e.g., caused by mycobacterial cells, residing within a host cell (e.g., a mammalian cell, e.g., immune cell, e.g., macrophage or dendritic cell). The compositions and methods include delivering a mixture of lytic enzymes to specifically target the cell envelope of a group of related bacterial species in the intracellular compartment (endosome, phagosome, lysosome, or cytosol) in which above mentioned orders of bacteria infect, grow, hide, and go quiescent.
Patent Information
| Application ID | 202447084968 |
| Invention Field | BIOTECHNOLOGY |
| Date of Application | 06/11/2024 |
| Publication Number | 47/2024 |
Inventors
| Name | Address | Country | Nationality |
|---|---|---|---|
| HOLDER, Jason | 180 Bradlee Ave. Swampscott, MA 01907 | U.S.A. | U.S.A. |
| BARTLETT, Helen | 128 Josephine Ave. Somerville, MA 02144 | U.S.A. | U.S.A. |
| BARRIOS, Sonia | 30 Franklin Street, Unit 411 Malden, MA 02148 | U.S.A. | U.S.A. |
| DAWSON, Clinton, C. | 18 Rowell Street Amesbury, MA 01913 | U.S.A. | U.S.A. |
| SOLOMON, Keith | 75 Child St. Hyde Park, MA 02136 | U.S.A. | U.S.A. |
| GLICKMAN, Cody | 5372 S Geneva Way Englewood, CO 80111 | U.S.A. | U.S.A. |
Applicants
| Name | Address | Country | Nationality |
|---|---|---|---|
| ENDOLYTIX TECHNOLOGY, INC. | 48 Dunham Ridge, Suite 5850 Beverly, MA 01915 | U.S.A. | U.S.A. |
Documents
| Name | Date |
|---|---|
| 202447084968-COMPLETE SPECIFICATION [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-DECLARATION OF INVENTORSHIP (FORM 5) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-DRAWINGS [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-FORM 1 [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-FORM 18 [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-PRIORITY DOCUMENTS [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-REQUEST FOR EXAMINATION (FORM-18) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084968-Sequence Listing in PDF [06-11-2024(online)].pdf | 06/11/2024 |
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