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BREATH-BASED MULTI-GAS ANALYZER FOR NON-INVASIVE HEALTH SCREENING AND METABOLIC ASSESSMENT

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BREATH-BASED MULTI-GAS ANALYZER FOR NON-INVASIVE HEALTH SCREENING AND METABOLIC ASSESSMENT

ORDINARY APPLICATION

Published

date

Filed on 5 November 2024

Abstract

The development and application of breath analysis sensors for detecting key biomarkers, including acetone, carbon dioxide (CO2), isoprene and ammonia, in exhaled air. The increasing interest in non-invasive diagnostic methods has highlighted the potential of breath analysis as a valuable tool for monitoring metabolic and respiratory health. This research utilizes a various types of sensor array, which is capable of identifying specific volatile organic compounds (VOCs) associated with various physiological conditions. Through a systematic evaluation of sensor performance, including sensitivity, selectivity, and response time, the study demonstrates the ability of these sensors to accurately detect and quantify the concentration of each target biomarker. The results indicate that elevated levels of acetone may correlate with diabetes, while changes in CO2 levels can reflect respiratory function. Additionally, the presence of isoprene may indicate metabolic activity, and ammonia levels can provide insights into kidney and liver health. The integration of these sensors into a breath analysis device holds promise for real-time health monitoring, enabling early diagnosis and management of various medical conditions. This research contributes to the growing field of non-invasive diagnostics, offering a novel approach to health assessment through the analysis of exhaled breath. The focus of future work will be on improving sensor accuracy and creating interfaces that are user-friendly for clinical and personal health applications. KEYWORDS: Non-invasive, Exhaled breath, Acetone, C02, Isoprene, Ammonia

Patent Information

Application ID202441084466
Invention FieldBIO-MEDICAL ENGINEERING
Date of Application05/11/2024
Publication Number46/2024

Inventors

NameAddressCountryNationality
S.RAVEENASRI SHAKTHI INSTITUTE OF ENGINEERING & TECHNOLOGY, COIMBATORE-641062.IndiaIndia
S.ROHINISRI SHAKTHI INSTITUTE OF ENGINEERING & TECHNOLOGY, COIMBATORE-641062.IndiaIndia
J.RONAL NIWARDSRI SHAKTHI INSTITUTE OF ENGINEERING & TECHNOLOGY, COIMBATORE-641062.IndiaIndia
R.SAHANASRI SHAKTHI INSTITUTE OF ENGINEERING & TECHNOLOGY, COIMBATORE-641062.IndiaIndia

Applicants

NameAddressCountryNationality
Dr. S.RAJALAXMISRI SHAKTHI INSTITUTE OF ENGINEERING & TECHNOLOGY, COIMBATORE-641062.IndiaIndia

Specification

PREAMBLE TO THE DESCRIPTION
A Breath-based Multi-Gas Analyzer is an innovative, non-invasive device designed to analyze multiple gases in a person's exhaled breath to provide realtime health insights. This technology utilizes "advanced sensors" to detect specific gases, such as carbon dioxide and acetone, each serving as biomarkers associated with various health conditions like "respiratory, metabolic, and gastrointestinal disorders".

2. The analyzer is a potential game-changer for "early diagnosis" and "continuous health monitoring". By examining these biomarkers, it enables "early detection" of health issues, allowing for timely interventions. This device is especially useful in settings where traditional diagnostic methods, like blood tests, are impractical due to being "invasive, costly, or uncomfortable".

3. The multi-gas analyzer supports preventive care and at-home health checks through affordable monitoring, helping with personalized health management and reducing the burden on healthcare facilities.
FORM 2

DESCRIPTION

1. A Breath-based Multi-Gas Analyzer is a medical device designed to analyze exhaled breath and provide real-time data on various gases like carbon dioxide (CO2), acetone and other volatile organic compounds. These gases serve as biomarkers for specific health conditions, including metabolic disorders, respiratory diseases, liver function abnormalities, and gastrointestinal issues.

2. This non-invasive device offers a user-friendly alternative to traditional methods such as blood tests or imaging, allowing for quick, affordable, and convenient health monitoring. With its sensors and data processing capabilities, the analyzer identifies gas levels and compares them to standard health ranges, alerting users and healthcare providers to potential issues.

3. The analyzer supports early diagnosis and ongoing health monitoring, providing a valuable tool for preventive care and personalized health assessments, especially in settings where access to healthcare might be limited.

Problem Description:
1. Many health assessments require invasive procedures, causing discomfort and inconvenience for patients.

2. Traditional metabolic and respiratory assessments can take time, delaying diagnosis and treatment.
Existing tools may not effectively capture early
indicators of metabolic. disorders.

The objectives of this invention are,
To create a device that uses exhaled breath to assess health, reducing the need for invasive methods like blood tests.

2. To provide immediate feedback on metabolic markers, allowing for regular and convenient health checks.

3. To enable early detection of conditions (e.g., diabetes, respiratory issues, liver & renal function) and monitor changes to track treatment efficacy.

4. To make the device compact, portable, and easy to use, which will make it accessible for frequent personal health monitoring.




SUMMARY
This research focuses on developing a breath analysis device that non-invasively assesses health by detecting key biomarkers such as acetone, carbon dioxide (CO2), isoprene and ammonia in exhaled air. By employing a specialized sensor array, the device aims to provide immediate feedback on metabolic markers, facilitating regular health checks without.the need for invasive blood tests.

2. The study demonstrates the sensors' high sensitivity and specificity in identifying trace levels of these volatile organic compounds (VOCs), enabling early detection of conditions such as diabetes, respiratory issues, and liver function abnormalities.

3. With the capability for near-instantaneous analysis, the device allows for real-time health monitoring and timely decision-making. Compact and user-friendly, it is designed for both clinical and personal health applications, making it accessible for frequent monitoring.

4. Future work will focus on enhancing sensor accuracy and developing intuitive interfaces to further improve user experience. Breath analysis is now recognized as a valuable tool in non-invasive diagnostics through this innovative approach.

CONCLUSION

The development of a breath analysis device utilizing advanced sensors for detecting key biomarkers represents a significant advancement in non-invasive health monitoring. By providing real-time feedback on metabolic markers and enabling early detection of various health conditions, this device offers a practical alternative to traditional invasive methods. Its compact and user-friendly design enhances accessibility for both clinical and personal health applications. Future enhancements aimed at improving sensor accuracy and interface usability will further solidify its role in proactive health management, making breath analysis an invaluable tool in modern diagnostics.
Advantages of creating this are as follows:

These advantages aim to enhance the Breath analysis using various types of sensors offers several advantages in medical diagnostics, environmental monitoring, and health management.

1. By analyzing multiple gases in a single breath sample, this technology can provide a holistic view of a patient's metabolic status and overall health, enabling the detection of various conditions simultaneously.

2. The non-invasive nature of breath analysis eliminates the discomfort and risks associated with blood draws and other invasive procedures, making it more appealing for regular health check-ups.

3. Breath-based analyzers can deliver quick results, facilitating timely medical decisions, which is crucial for conditions that require prompt treatment.
4. Breath analyzers can be linked to telehealth platforms, allowing for remote consultations and continuous health monitoring, which is particularly useful in rural or ^ -underseverel regions.


CLAIMS
We Claim,
1. The mouth air analysis will be a feasible biomarker for various traces of exhaled gases in which each gas will signify the outbreak of certain health condition. This product customizes health screening by-self pertaining to organs including lungs, kidney, liver and metabolism.

2. Provides near-instantaneous analysis of breath samples, delivering real-time data that allows for immediate health assessments and decision-making.

3. Offers a completely non-invasive method for monitoring health indicators related to metabolic processes (e.g., diabetes management via acetone levels, stress assessment through isoprene, kidney function through ammonia, and alcohol monitoring via ethanol)

4. Compact and lightweight for ease of use in clinical and at-home settings, with a simple interface that allows non-specialists to operate the device effectively.

Documents

NameDate
202441084466-Form 1-051124.pdf08/11/2024
202441084466-Form 2(Title Page)-051124.pdf08/11/2024
202441084466-Form 3-051124.pdf08/11/2024
202441084466-Form 5-051124.pdf08/11/2024

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