AN IOT-BASED SYSTEM FOR ANTIBACTERIAL PHOTODYNAMIC INACTIVATION AND METHOD THEREOF

Abstract

ABSTRACT The present disclosure envisages an Internet of Things (IOT)-based system (100) for antibacterial photodynamic inactivation and method (300) thereof. The Internet of Things (IoT)-based system (100) for antibacterial photodynamic inactivation comprises an enclosed light chamber (102) equipped with an openable door (102a) on a front side, an display unit (104) to show values of said plurality of parameters during the system operation,to support an illumination source (104a), a height-adjustable unit (106) to adjust the height of said illumination source 104a, a temperature regulation unit (108) to maintain the operating temperature within the chamber (102), a plurality of sensors (110) to monitor light irradiance and operating temperature, a microcontroller (112) to receive control inputs from a user for controlling a plurality of parameters and a web platform to monitor and record the values during the system operation. The web platform is being configured to operate with an IoT suite.

Specification

Description:FIELD
[0001] The present disclosure relates, in general, to the field of the Internet of Things (IoT).
[0002] More particularly, embodiments of the present disclosure relate to an Internet of Things (IoT)-based system for antibacterial photodynamic inactivation and method 5 thereof.
DEFINITION
[0003] As used in the present disclosure, the following terms are generally intended to have the meaning as set forth below, except to the extent that the context in which they are used to indicate otherwise. 10
[0004] "Internet of Things (IoT)" refers to devices with sensors, processing ability, software and other technologies that connect and exchange data with other devices and systems over the Internet or other communication networks. The Internet of Things (IoT) encompasses electronics, communication, and computer science engineering. "Internet of things" has been considered a misnomer because devices do not need to be connected to 15 the public internet; they only need to be connected to a network and be individually addressable.
"Antibacterial Photodynamic inactivation" refers to the use of light and a photosensitiser (PS) to generate reactive oxygen species (ROS) that can eliminate/reduce microorganisms in the field of illumination. PDI is based on the photosensitization of 20 bacteria with endogenous or exogenous compounds referred to as photosensitizers (PSs). The energy of the photons is absorbed by the photosensitizer and the generation of reactive oxygen species (ROS) including singlet oxygen. Cell death is subsequently triggered by lethal oxidative stress that is induced by irradiation of the infected area with light of a resonant wavelength, typically in the visible wavelength range (300-700 nm). 25
BACKGROUND
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[0005] The background information herein below relates to the present disclosure but is not necessarily prior art.
[0006] Antibacterial photodynamic inactivation is a technique of eliminating microorganisms by triggering oxidative stress within their cells. It traditionally relies on antibiotics, which work by targeting specific bacterial processes, such as cell wall 5 synthesis or protein production, to kill or inhibit the growth of bacteria. However, with the rise of antibiotic resistance, alternative approaches are becoming increasingly important.
[0007] The need for effective antibacterial inactivation has never been more critical due to the alarming rise of antibiotic-resistant bacteria. Infections that were once easily 10 treatable with standard antibiotics are now becoming life-threatening, creating a global health crisis. This growing resistance not only increases the duration and severity of illnesses but also leads to higher healthcare costs and mortality rates.
[0008] Existing solutions in antibacterial inactivation encompass a range of approaches designed to combat bacterial infections and address the growing issue of 15 antibiotic resistance. Traditional antibiotics remain a cornerstone, but their effectiveness is waning due to widespread resistance. To counter this, researchers are exploring alternative therapies such as bacteriophage therapy, which uses viruses that specifically target and kill bacteria and antimicrobial peptides that disrupt bacterial cell membranes. Antibacterial photodynamic inactivation (PDI) is another promising solution, employing 20 light-activated compounds to generate reactive oxygen species that destroy bacterial cells. Additionally, the development of new-generation antibiotics with novel mechanisms of action aims to outpace resistance. Combination therapies, where antibiotics are used alongside other agents like PDI or immune modulators, also offer enhanced efficacy and reduced likelihood of resistance. PDI can also be employed for sterilisation and 25 disinfection purposes.
[0009] While antibacterial photodynamic inactivation (PDI) offers a promising alternative to traditional methods, it is not without its drawbacks. One major limitation is that the cost and complexity of the equipment required for PDI can limit its widespread adoption, especially in low-resource settings. 30
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[0010] Therefore, there is a need to develop an IOT-based system for antibacterial photodynamic inactivation and a method thereof that alleviates the drawback mentioned above.
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OBJECTS
[0011] Some of the objects of the present disclosure, which at least one embodiment herein satisfies, are as follows.
[0012] It is an object of the present disclosure to ameliorate one or more problems of the prior art or to at least provide a useful alternative. 10
[0013] The main object of the present disclosure is to provide an Internet of Things (IoT)-based system for antibacterial photodynamic inactivation and method thereof.
[0014] Another object of the present disclosure is to provide a system for antibacterial photodynamic inactivation with real-time monitoring of the multiple parameters used for inactivation. 15
[0015] Another object of the present disclosure is to provide a system for antibacterial photodynamic inactivation that allows adjustments for the multiple parameters used for inactivation.
[0016] Another object of the present disclosure is to provide a system for antibacterial photodynamic inactivation that incorporates optional password protection to 20 secure measurement settings of the multiple parameters used for inactivation.
[0017] Another object of the present disclosure is to provide a system for antibacterial photodynamic inactivation that maintains an optimal temperature.
[0018] Another object of the present disclosure is to provide a system for antibacterial photodynamic inactivation providing experimental data, visualizations, and 25 controls.
[0019] Another object of the present disclosure is to provide a system for antibacterial photodynamic inactivation that is environment-friendly.
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[0020] Another object of the present disclosure is to provide a cost-effective antibacterial photodynamic inactivation.
[0021] Another object of the present disclosure is to provide antibacterial photodynamic inactivation with improved efficiency.
[0022] Other objects and advantages of the present disclosure will be more apparent 5 from the following description when read in conjunction with the accompanying figures, which are not intended to limit the scope of the present disclosure.
SUMMARY 10
[0023] This summary is provided to introduce concepts related to an Internet of Things (IoT)-based system for antibacterial photodynamic inactivation and method thereof. The concepts are further described below in the following detailed description. This summary is not intended to identify essential features of the claimed subject matter nor is it intended for use in determining or limiting the scope of the claimed subject 15 matter.
[0024] The present disclosure envisages an Internet of Things (IoT)-based system for antibacterial photodynamic inactivation.
[0025] The Internet of Things (IoT)-based system for antibacterial photodynamic inactivation, said system comprises an enclosed light chamber, an illumination holder, a 20 height-adjustable unit, a temperature regulation unit, a plurality of sensors, a microcontroller, a display unit, and a web platform. The enclosed light chamber is equipped with an openable door on the front side.
[0026] The illumination holder is configured to support an illumination source configured within said chamber to emit light within the interior of said chamber within a 25 predefined wavelength range.
[0027] The height-adjustable unit is configured within said chamber to cooperate with said illumination holder to adjust the height of said illumination source for providing illumination within a predefined illumination range.
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[0028] The temperature regulation unit includes one or more fans and is configured within said chamber to maintain the operating temperature within the chamber during system operation.
[0029] The plurality of sensors is configured within said chamber to monitor light irradiance and operating temperature within said chamber. 5
[0030] The microcontroller is configured on the front side of said chamber and cooperating with said illumination source, said height-adjustable unit, said plurality of sensors, and said temperature regulation unit, to receive control inputs from a user for controlling a plurality of parameters. The plurality of parameters includes said irradiance from said illumination source, said operating temperature inside the chamber, time of 10 exposure of light from said illumination source and said height of illumination source.
[0031] The display unit is configured with said chamber and cooperating with said microcontroller to show values of said plurality of parameters during the system operation.
[0032] The web platform is configured to cooperate with said microcontroller and 15 said display unit to monitor and record the values during the system operation. The web platform is being configured to operate with an IoT suite.
[0033] In an aspect, the interior of the enclosed light chamber has a white background.
[0034] In an aspect, the illumination source includes an array of light emitting diodes 20 (LEDs), wherein said array operates at a voltage ranging from 220 V to 250 V alternate current, which is converted to 12V DC for the system operation.
[0035] In an aspect, the display unit is configured to simultaneously show the following values:
? irradiance in mW/cm²; 25
? wavelength in nm;
? temperature in °C;
? height of illumination in cm; and ? time of exposure in minutes.
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[0036] In an aspect, the chamber is a closed structure to minimize contamination during the photodynamic inactivation process.
[0037] In an aspect, the system further comprising a password protection feature to prevent unauthorized changes to the control settings during experiments, ensuring the accuracy of measurements. 5
[0038] In an aspect, the IoT suite is configured to monitor and record the following parameters during the experiment
? irradiance levels;
? wavelength of emitted light;
? temperature inside the chamber; 10
? time of exposure; and
? height of illumination.
[0039] In an aspect, the illumination holder is configured to accommodate different types of illumination sources to accommodate different therapeutic applications requiring specific wavelengths of light. 15
[0040] In an aspect, the plurality of sensors includes a sensor for irradiance measurement that is AS7341 and a sensor for operating temperature measurement that is LM35.
[0041] In an aspect, based on control inputs received from the user, said microcontroller is configured to control: 20
? said height-adjustable unit to adjust the height of said illumination source to adjust said irradiance between 20.00 mW/cm² to 50.00 mW/cm² from said illumination source,
? an input supply of said illumination source to adjust the time of exposure of light from said illumination source from 0 to 300 minutes, 25
? said temperature regulation unit to adjust the operating temperature inside the chamber, and
? said height-adjustable unit to adjust the height of illumination in the predefined illumination range of 2 cm to 10 cm.
[0042] In an aspect, the pre-defined wavelength range includes 300 nm to 700 nm. 30
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[0043] The present disclosure further envisages a method for antibacterial inactivation using the Internet of Things (IoT)-based system for antibacterial photodynamic inactivation. The method includes the following steps:
? adjusting the height of said illumination source within said chamber to achieve irradiance levels desired by the user; 5
? setting the time of exposure and irradiance using said microcontroller;
? activating said illumination source to emit light at a wavelength selected by the user for photodynamic inactivation;
? maintaining the operating temperature selected by the user within the chamber using the temperature regulation unit; 10
? monitoring and recording the values of said plurality of parameters using the IoT suite during the antibacterial inactivation process; and
? display a real-time plurality of parameters on the display unit, including irradiance, wavelength, operating temperature, time of exposure, and height of illumination. 15
BRIEF DESCRIPTION OF THE ACCOMPANYING DRAWING
[0044] An Internet of Things (IoT)-based system for antibacterial photodynamic inactivation and the method thereof of the present disclosure will now be described with 20 the help of the accompanying drawing, in which: [0045] FIGURE 1 illustrates the perspective view of an Internet of Things (IoT)-based system for antibacterial photodynamic inactivation explaining the front view, left elevation and back view of the Internet of Things (IoT)-based system, in accordance with an embodiment of the present disclosure; 25 [0046] FIGURES 2A, 2B and 2C illustrate the front view, left elevation and back view of the Internet of Things (IoT)-based system for antibacterial photodynamic inactivation thermal with reference to FIGURE 1; and
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[0047] FIGURE 3 illustrates a method for antibacterial inactivation using the Internet of Things (IoT)-based system for antibacterial photodynamic inactivation, in accordance with an embodiment of the present disclosure.
LIST OF REFERENCE NUMERALS 5
100
Internet of Things (IoT)-based system
102
Enclosed light chamber
102a
Openable door
104
Display unit
104a
Illumination source
106
Height-adjustable unit
108
Temperature regulation unit
110
Plurality of sensors
112
Microcontroller
DETAILED DESCRIPTION
[0048] Embodiments, of the present disclosure, will now be described with reference to the accompanying drawing. 10
[0049] Embodiments are provided to thoroughly and fully convey the scope of the present disclosure to the person skilled in the art. Numerous details are set forth, relating to specific components and methods to provide a complete understanding of the embodiments of the present disclosure. It will be apparent to the person skilled in the art that the details provided in the embodiments should not be construed to limit the scope of 15 the present disclosure. In some embodiments, well-known apparatus structures, and well-known techniques are not described in detail.
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[0050] The terminology used, in the present disclosure, is only to explain a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure. As used in the present disclosure, the forms "a", "an", and "the" may be intended to include the plural forms as well, unless the context clearly suggests otherwise. The terms, "comprises", "comprising", "including" and "having" are open-ended 5 transitional phrases and therefore, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not forbid the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
[0051] When an element is referred to as being "embodied thereon", "engaged to", 10 "coupled to" or "communicatively coupled to" another element, it may be directly on, engaged, connected or coupled to the other element. As used herein, the term "and/or" includes any combinations of one or more of the associated listed elements.
[0052] While antibacterial photodynamic inactivation (PDI) offers a promising alternative to traditional antibiotics, it is not without its drawbacks. One major limitation 15 is its dependency on the penetration of light to activate the photosensitizing agent, which restricts its effectiveness to superficial or easily accessible infections and surfaces. This makes it challenging to treat deeper tissue infections or those in areas where light cannot easily reach. Additionally, the treatment's success is highly dependent on the precise delivery of the photosensitizer and the correct wavelength and intensity of light, which 20 can be difficult to control in different settings.
[0053] Moreover, the cost and complexity of the equipment required for PDI can limit its widespread adoption, especially in low-resource settings.
[0054] The present disclosure presents an Internet of Things (IOT) based system for antibacterial photodynamic inactivation. This system shows simultaneous visualization 25 of the time of exposure, light irradiation, voltage and temperature. This innovative approach utilizes environmentally friendly methods and the system has a provision for monitoring and recording the experiment using a web platform Nextler IoT suite. This system represents a significant advancement in antibacterial inactivation with multifaceted benefits. 30
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[0055] The present disclosure envisages an Internet of Things (IOT)-based system for antibacterial photodynamic inactivation and a method thereof. The Internet of Things (IoT) (100)-based system for antibacterial photodynamic inactivation is described with reference to FIGURES 1 to 2, in accordance with the present disclosure. Method for antibacterial inactivation using the Internet of Things (IoT)-based system for antibacterial 5 photodynamic inactivation is described with reference to FIGURE 3, in accordance with the present disclosure. [0056] FIGURE 1 illustrates the perspective view of an Internet of Things (IoT)-based system for antibacterial photodynamic inactivation explaining front view, left elevation and back view of the Internet of Things (IoT)-based system, in accordance with 10 an embodiment of the present disclosure.
[0057] The Internet of Things (IoT)-based system for antibacterial photodynamic inactivation is shown in FIGURE 1, as a representative design. The Internet of Things (IoT)-based system 100 for antibacterial photodynamic inactivation comprises an enclosed light chamber 102, an Display unit 104, a height-adjustable unit 106, a 15 temperature regulation unit 108, a plurality of sensors 110, a microcontroller 112 and a web platform. [0058] FIGURES 2A, 2B, and 2C illustrate the front view, left elevation and back view of the Internet of Things (IoT)-based system for antibacterial photodynamic inactivation thermal with reference to FIGURE 1. 20
[0059] The enclosed light chamber 102 is equipped with an openable door 102a on a front side.
[0060] The Display unit 104 is configured to display an illumination values 104a configured within said chamber 102 to emit light within an interior of said chamber 102 within a predefined wavelength range. 25
[0061] The height-adjustable unit 106 is configured within said chamber 102 to cooperate with said display unit 104 to adjust the height of said illumination source 104a for providing illumination within a predefined illumination range.
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[0062] The temperature regulation unit 108 includes one or more fans 108a and configured within said chamber 102 to maintain the operating temperature within the chamber 102 during system operation.
[0063] The plurality of sensors 110 is configured within said chamber 102 to monitor light irradiance and operating temperature within said chamber 102. 5
[0064] The microcontroller 112 is configured on the front side of said chamber 102 and cooperating with said illumination source 104a, said height-adjustable unit 106, said plurality of sensors 110, and said temperature regulation unit 108, to receive control inputs from a user for controlling a plurality of parameters. The plurality of parameters includes said irradiance from said illumination source 104a, said operating temperature 10 inside the chamber 102, time of exposure of light from said illumination source 104a, and said height of illumination source 104a.
[0065] The display unit 104 is configured with said chamber 102 and cooperating with said microcontroller 112 to show values of said plurality of parameters during the system operation. 15
[0066] The web platform is configured to cooperate with said microcontroller 112 and said display unit 104 to monitor and record the values during the system operation. The web platform is being configured to operate with an IoT suite.
[0067] In an aspect, the interior of the enclosed light chamber has a white background. 20
[0068] In an aspect, the illumination source includes an array of light emitting diodes (LEDs), and wherein said array operates at a voltage ranging from 220 V to 250 V alternate current, which is converted to 12V DC for the system operation.
[0069] In an aspect, the display unit is configured to simultaneously show the following values: 25
? irradiance in mW/cm²;
? wavelength in nm;
? temperature in °C;
? height of illumination in cm; and ? time of exposure in minutes. 30
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[0070] In an aspect, the chamber is a closed structure to minimize contamination during the photodynamic inactivation process.
[0071] In an aspect, the system further comprises a password protection feature to prevent unauthorized changes to the control settings during experiments, ensuring the accuracy of measurements. 5
[0072] In an aspect, the IoT suite is configured to monitor and record the following parameters during the experiment
? irradiance levels;
? wavelength of emitted light;
? temperature inside the chamber; 10
? time of exposure; and
? height of illumination.
[0073] In an aspect, the illumination holder is configured to accommodate different types of illumination sources to accommodate different therapeutic applications requiring specific wavelengths of light. 15
[0074] In an aspect, the plurality of sensors includes a sensor for irradiance measurement that is AS7341 and a sensor for operating temperature measurement that is LM35.
[0075] In an aspect, based on control inputs received from the user, said microcontroller is configured to control: 20
? said height-adjustable unit to adjust the height of said illumination source to adjust said irradiance between 20.00 mW/cm² to 50.00 mW/cm² from said illumination source,
? an input supply of said illumination source to adjust the time of exposure of light from said illumination source from 0 to 300 minutes, 25
? said temperature regulation unit to adjust the operating temperature inside the chamber, and
? said height-adjustable unit to adjust the height of illumination in the predefined illumination range of 2 cm to 10 cm.
[0076] In an aspect, the pre-defined wavelength range includes 300 nm to 700 nm. 30
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[0077] The system 100 allows real-time visualization of exposure time, light irradiation, voltage, and temperature. The approach utilizes green methods for antibacterial inactivation. The system 100 is designed to inactivate bacteria through photodynamic inactivation (PDT). This is achieved by using LED lights to irradiate the bacteria with specific wavelengths of light. The system 100 includes several features to 5 monitor and control the experimental conditions, ensuring precision and repeatability. [0078] FIGURE 3 illustrates a method 300 for antibacterial inactivation using the Internet of Things (IoT)-based system 100 for antibacterial photodynamic inactivation, in accordance with an embodiment of the present disclosure. The order in which the method 300 is described is not intended to be construed as a limitation, and any number of the 10 described method steps can be combined in any appropriate order to carry out the method 300 or an alternative method. Additionally, individual steps may be deleted from the method 300 without departing from the scope of the subject matter described herein. The method 300 for antibacterial inactivation is executed by the Internet of Things (IoT)-based system 100. The method 300 includes the following steps: 15 [0079] In method step 302, the method 300 comprises adjusting the height of said illumination source 104a within said chamber 102 to achieve irradiance levels desired by the user. [0080] In method step 304, the method 300 comprises setting the time of exposure and irradiance using said microcontroller 112. 20 [0081] In method step 306, the method 300 comprises activating said illumination source 104a to emit light at a wavelength selected by the user for photodynamic inactivation. [0082] In method step 308, the method 300 comprises maintaining the operating temperature selected by the user within the chamber 102 using the temperature regulation 25 unit 108. [0083] In method step 310, the method 300 comprises monitoring and recording the values of said plurality of parameters using the IoT suite during the antibacterial inactivation process.
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[0084] In method step 312, the method 300 comprises displaying real-time plurality of parameters on the display unit 104, including irradiance, wavelength, operating temperature, time of exposure, and height of illumination
[0085] The foregoing description of the embodiments has been provided for purposes of illustration and is not intended to limit the scope of the present disclosure. Individual 5 components of a particular embodiment are generally not limited to that particular embodiment but, are interchangeable. Such variations are not to be regarded as a departure from the present disclosure, and all such modifications are considered to be within the scope of the present disclosure.
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APPLICATIONS
[0086] The Internet of Things (IoT)-based system 100 for antibacterial photodynamic inactivation and method 300 thereof have a wide range of uses, applications, and benefits in the field of Internet of Things (IoT). Some of the major applications and potential uses for the present invention include: 15
1. Biomedical Applications: The antibacterial properties make it suitable for wound healing and oral healthcare
2. Healthcare and Food Industry: Food surface decontamination, equipment sterilization thereby ensuring hygiene, and safety by inactivating bacteria.
3. Water treatment: Offering chemical free water purification systems to 20 eliminate bacterial contaminants
4. Industrial and Academic Research: Provides a robust platform for studying modern green blend approaches and characterizing their properties and applications.
5. Collaboration Across Disciplines: Facilitates research collaborations in 25 microbiology, biotechnology, and other disciplines of biological sciences.
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TECHNICAL ADVANCEMENTS AND ECONOMIC SIGNIFICANCE
[0087] The present disclosure described herein above has several technical advantages including, but not limited to, an Internet of Things (IoT)-based system 100 for antibacterial photodynamic inactivation and method 300 thereof, which:
? provides the user(s) with a system 100 including the Nextler IoT suite for 5 monitoring and recording experiments represents a significant advancement;
? provides the user(s) with a system 100 that allows for remote observation and data collection, facilitating better data management and collaboration;
? provides the user(s) with a system 100 that ensures that experiment 10 settings are not altered inadvertently, maintaining experimental integrity;
? provides the user(s) with a system 100 with real-time display of irradiance, wavelength, temperature, and height provides comprehensive monitoring capabilities;
? provides the user(s) with a system 100 that minimizes contamination risk 15 and enhances the efficiency of light reflection, increasing the effectiveness of the LED light in the chamber; and
? provides the user(s) with a system 100 that offers flexibility in conducting experiments with different light wavelengths, broadening the range of possible applications. 20
[0088] The present disclosure described herein above has several economic advantages including, but not limited to:
? is cost-effective, compared to the state-of-the-art equipment used for antibacterial photodynamic inactivation;
? is light-weight, compared to the state-of-the-art equipment used for 25 antibacterial photodynamic inactivation;
? is energy-saving, compared to the state-of-the-art equipment used for antibacterial photodynamic inactivation;
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? is efficient, compared to the state-of-the-art equipment used for antibacterial photodynamic inactivation; and
? is compact, compared to the state-of-the-art equipment used for antibacterial photodynamic inactivation.
[0089] The embodiments herein and the various features and advantageous details thereof 5 are explained with reference to the non-limiting embodiments in the following description. Descriptions of well-known components and processing techniques are omitted so as to not unnecessarily obscure the embodiments herein. The examples used herein are intended merely to facilitate an understanding of ways in which the embodiments herein may be practiced and to further enable those of skill in the art to 10 practice the embodiments herein. Accordingly, the examples should not be construed as limiting the scope of the embodiments herein.
[0090] The foregoing description of the specific embodiments so fully reveal the general nature of the embodiments herein that others can, by applying current knowledge, readily modify and/or adapt for various applications such specific embodiments without 15 departing from the generic concept, and, therefore, such adaptations and modifications should and are intended to be comprehended within the meaning and range of equivalents of the disclosed embodiments. It is to be understood that the phraseology or terminology employed herein is for the purpose of description and not of limitation. Therefore, while the embodiments herein have been described in terms of preferred embodiments, those 20 skilled in the art will recognize that the embodiments herein can be practiced with modification within the spirit and scope of the embodiments as described herein.
[0091] The use of the expression "at least" or "at least one" suggests the use of one or more elements or ingredients or quantities, as the use may be in the embodiment of the disclosure to achieve one or more of the desired objects or results. 25
[0092] Any discussion of documents, acts, materials, devices, articles or the like that has been included in this specification is solely for the purpose of providing a context for the disclosure. It is not to be taken as an admission that any or all of these matters form a part of the prior art base or were common general knowledge in the field relevant to the disclosure as it existed anywhere before the priority date of this application. 30
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[0093] The numerical values mentioned for the various physical parameters, dimensions or quantities are only approximations and it is envisaged that the values higher/lower than the numerical values assigned to the parameters, dimensions or quantities fall within the scope of the disclosure, unless there is a statement in the specification specific to the contrary. 5
[0094] While considerable emphasis has been placed herein on the components and component parts of the preferred embodiments, it will be appreciated that many embodiments can be made and that many changes can be made in the preferred embodiments without departing from the principles of the disclosure. These and other changes in the preferred embodiment as well as other embodiments of the disclosure will 10 be apparent to those skilled in the art from the disclosure herein, whereby it is to be distinctly understood that the foregoing descriptive matter is to be interpreted merely as illustrative of the disclosure and not as a limitation. , Claims:WE CLAIM: 1. An Internet of Things (IOT) based system (100) for antibacterial photodynamic inactivation, said system (100) comprises:
an enclosed light chamber (102) having an openable door (102a) on a front side; 5
a display unit (104) to support an illumination source (104a) configured within said chamber (102) to emit light within an interior of said chamber (102) within a predefined wavelength range;
a height-adjustable unit (106) configured within said chamber (102) to cooperate with said display unit (104) to adjust the height of said illumination 10 source (104a) for providing illumination within a predefined illumination range;
a temperature regulation unit (108) including one or more fans (108a) configured within said chamber (102) to maintain the operating temperature within the chamber (102) during system operation;
a plurality of sensors (110) configured within said chamber (102) to 15 monitor light irradiance and operating temperature within said chamber (102);
a microcontroller (112) configured on the front side of said chamber (102) and cooperating with said illumination source (104a), said height-adjustable unit (106), said plurality of sensors (110), and said temperature regulation unit (108), to receive control inputs from a user for controlling a plurality of parameters, said 20 the plurality of parameters including said irradiance from said illumination source (104a), said operating temperature inside the chamber (102), time of exposure of light from said illumination source (104a), and said height of illumination source (104a);
a display unit (104) configured with said chamber (102) and cooperating 25 with said microcontroller (112) to show values of said plurality of parameters during the system operation; and
a web platform configured to cooperate with said microcontroller (112) and said display unit (104) to monitor and record the values during the system
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operation, wherein said web platform being configured to operate with an IoT suite. 2. The system (100) as claimed in claim 1, wherein the interior of the enclosed light chamber (102) has a white background. 3. The system (100) as claimed in claim 1, wherein the illumination source (104a) 5 includes an array of light emitting diodes (LEDs), and wherein said array operates at a voltage ranging from 220 V to 250 V alternate current, which is converted to 12V DC for the system operation. 4. The system (100) as claimed in claim 1, wherein the display unit (104) is configured to simultaneously show the following values: 10
? irradiance in mW/cm²;
? wavelength in nm;
? temperature in °C;
? height of illumination in cm; and ? time of exposure in minutes. 15 5. The system (100) as claimed in claim 1, wherein said chamber (102) is a closed structure to minimize contamination during the photodynamic inactivation process. 6. The system (100) as claimed in claim 1, further comprises a password protection feature to prevent unauthorized changes to the control settings during experiments, ensuring the accuracy of measurements. 20 7. The system (100) of claim 1, wherein the IoT suite is configured to monitor and record the following parameters during the experiment:
? irradiance levels;
? wavelength of emitted light;
? temperature inside the chamber; 25
? time of exposure; and
? height of illumination.
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8. The system (100) as claimed in claim 1, wherein said display unit (104) is configured to accommodate different types of illumination sources (104a) to to accommodate different therapeutic applications requiring specific wavelengths of light. 9. The system (100) as claimed in claim 1, wherein said plurality of sensors (110) includes a sensor for irradiance measurement that is AS7341 and a sensor for 5 operating temperature measurement that is LM35. 10. The system (100) as claimed in claim 1, wherein based on control inputs received from the user, said microcontroller (112) is configured to control: ? said height-adjustable unit (106) to adjust the height of said illumination source (104a) to adjust said irradiance between 20.00 mW/cm² to 50.00 mW/cm² from 10 said illumination source (104a), ? an input supply of said illumination source (104a) to adjust the time of exposure of light from said illumination source (104a) from 0 to 300 minutes, ? said temperature regulation unit (108) to adjust the operating temperature inside the chamber (102), and 15 ? said height-adjustable unit (106) to adjust the height of illumination in the predefined illumination range of 2 cm to 10 cm. 11. The system (100) as claimed in claim 1, wherein said predefined wavelength range includes 300 nm to 700 nm. 12. A method (300) for antibacterial inactivation using the system (100) as claimed in 20 claim 1, said method comprising:
adjusting the height of said illumination source (104a) within said chamber to achieve irradiance levels desired by the user;
setting the time of exposure and irradiance using said microcontroller (112); activating said illumination source (104a) to emit light at a wavelength 25 selected by the user for photodynamic inactivation; maintaining the operating temperature selected by the user within the chamber (102) using the temperature regulation unit (108);
monitoring and recording the values of said plurality of parameters using the IoT suite during the antibacterial inactivation process; and 30
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displaying a real-time plurality of parameters on the display unit (104), including irradiance, wavelength, operating temperature, time of exposure, and height of illumination.
_______________________________
MOHAN RAJKUMAR DEWAN, IN/PA - 25
OF R.K. DEWAN & CO.
AUTHORIZED AGENT OF APPLICANT
TO,
THE CONTROLLER OF PATENTS
THE PATENT OFFICE, AT NEW DELHI

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