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ADENO-ASSOCIATED VIRUS VARIANT CAPSIDS WITH IMPROVED LUNG TROPISM AND USES THEREOF
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ADENO-ASSOCIATED VIRUS VARIANT CAPSIDS WITH IMPROVED LUNG TROPISM AND USES THEREOF
PCT NATIONAL PHASE APPLICATION
Published
Filed on 6 November 2024
Abstract
The present disclosure provides a variant AAV capsid protein that confers tropism to lung cells and recombinant adeno-associated viruses comprising the variant AAV capsid protein and pharmaceutical compositions comprising same and their use in the delivery of heterologous nucleic acids to lung cells for the treatment of pulmonary disorders.
Patent Information
| Application ID | 202447084998 |
| Invention Field | BIOTECHNOLOGY |
| Date of Application | 06/11/2024 |
| Publication Number | 46/2024 |
Inventors
| Name | Address | Country | Nationality |
|---|---|---|---|
| FRANCIS, Peter | c/o 4D Molecular Therapeutics Inc. 5858 Horton Street, Suite 455 Emeryville, California 94608 | U.S.A. | U.S.A. |
| KOTTERMAN, Melissa A. | c/o 4D Molecular Therapeutics Inc. 5858 Horton Street, Suite 455 Emeryville, California 94608 | U.S.A. | U.S.A. |
| NYE, Julie | c/o 4D Molecular Therapeutics Inc. 5858 Horton Street, Suite 455 Emeryville, California 94608 | U.S.A. | U.S.A. |
| CROZE, Roxanne | c/o 4D Molecular Therapeutics Inc. 5858 Horton Street, Suite 455 Emeryville, California 94608 | U.S.A. | U.S.A. |
Applicants
| Name | Address | Country | Nationality |
|---|---|---|---|
| 4D MOLECULAR THERAPEUTICS INC. | 5858 Horton Street, Suite 455 Emeryville, California 94608 | U.S.A. | U.S.A. |
Documents
| Name | Date |
|---|---|
| 202447084998-COMPLETE SPECIFICATION [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-DECLARATION OF INVENTORSHIP (FORM 5) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-FORM 1 [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-FORM 18 [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-PRIORITY DOCUMENTS [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-PROOF OF RIGHT [06-11-2024(online)].pdf | 06/11/2024 |
| 202447084998-Sequence Listing in PDF [06-11-2024(online)].pdf | 06/11/2024 |
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