A METHOD FOR PREPARING DRUG DELIVERY FORMULATION USING ALGAL METABOLITES FOR TREATING CANCER

Abstract

ABSTRACT A method (100) for preparing drug delivery formulation using algal metabolites for treating cancer. Further, the method (100) comprising cultivating algal species in a controlled environment to produce metabolites effective in anti-cancer activity. Further, harvesting the algal metabolites from the cultivated algal species. Further, extracting and purifying the algal metabolites using a solvent extraction process to obtain an anti-cancer bioactive fraction. Further, encapsulating the bioactive fraction into a drug delivery carrier to enhance bioavailability, wherein the drug delivery carrier is selected from nanoparticles, liposomes, or hydrogels. Further, formulating the encapsulated bioactive fraction into a dosage form suitable for administration, wherein the dosage form is selected from oral, topical, or injectable formulation.

Specification

Description:FIELD OF THE DISCLOSURE
[0001] This invention generally relates to a field of therapeutic formulation and, in particular to a method for preparing drug delivery formulation using algal metabolites for treating cancer.
BACKGROUND

[0002] The subject matter discussed in the background section should not be assumed to be prior art merely as a result of its mention in the background section. Similarly, a problem mentioned in the background section or associated with the subject matter of the background section should not be assumed to have been previously recognized in the prior art. The subject matter in the background section merely represents different approaches, which in and of themselves may also correspond to implementations of the claimed technology.
[0003] The demand for novel anti-cancer therapies derived from natural products has significantly increased, driven by the limitations and adverse effects of conventional chemotherapeutic agents. Natural products from marine sources, particularly algae, ha , Claims:1. A method (100) for preparing drug delivery formulation using algal metabolites for treating cancer, the method comprising:
cultivating algal species in a controlled environment to produce metabolites effective in anti-cancer activity, at step 102;
harvesting the algal metabolites from the cultivated algal species, at step 104;
extracting and purifying the algal metabolites using a solvent extraction process to obtain an anti-cancer bioactive fraction, at step 106;
encapsulating the bioactive fraction into a drug delivery carrier to enhance bioavailability, wherein the drug delivery carrier is selected from nanoparticles, liposomes, or hydrogels, at step 108; and
formulating the encapsulated bioactive fraction into a dosage form suitable for administration, wherein the dosage form is selected from oral, topical, or injectable formulation, at step 110.

2. The method (100) as claimed in claim 1, wherein the algal metabolites comprises Amphidinol from Amphidinium carterae, fucoxanthin from Chaetoceros cal

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